梅毒感染孕妇结局调查研究

发布时间：2018-07-26 17:46

【摘要】：目的探讨梅毒感染孕妇及新生儿状况,从而探寻降低新生儿梅毒发病率、确保新生儿健康的临床医学方法。方法选择2013年1月-2015年1月60例医院接诊的梅毒感染孕妇进行研究,采用随机数表法将其平均分为观察组与对照组各30例,观察组孕妇采取全程抗梅毒治疗,对照组孕妇未采取任何治疗,对比分析两组孕妇的相关指标。结果妊娠不良结局发生率观察组为3.33%、对照组为26.67%,两组比较差异有统计学意义(χ2=4.7835,P0.05);新生儿不良结局发生率观察组为6.70%、对照组为33.33%,两组比较差异有统计学意义(χ2=4.5000,P0.05);两组新生儿平均孕周、体质量和新生儿疾病比较,差异有统计学意义(P0.05);新生儿并发症发生率观察组为10.00%、对照组为66.67%,两组比较差异有统计学意义(χ2=9.4810,P0.05)。结论对梅毒感染孕妇进行常规检查以及时有效地对其采取规范化的抗梅治疗,可有效减少妊娠不良结局,并可降低新生儿先天梅毒、疾病和并发症的发生。
[Abstract]:Objective to explore the clinical medical methods to reduce the incidence of syphilis in pregnant women and newborns with syphilis infection and to ensure the health of newborns. Methods from January 2013 to January 2015, 60 pregnant women with syphilis were randomly divided into two groups: the observation group (n = 30) and the control group (n = 30). The pregnant women in the control group did not take any treatment, and the related indexes of the two groups were compared and analyzed. Results the incidence of adverse outcome of pregnancy was 3.33 in the observation group and 26.67 in the control group, the difference between the two groups was statistically significant (蠂 ~ 2 ~ (2) 4.7835), the incidence rate of adverse outcome of newborn was 6.70 in the observation group and 33.33 in the control group, the difference between the two groups was statistically significant (蠂 ~ (2 +) 4.5000), the average gestational weeks of the two groups were significantly higher than that of the control group (P < 0.05). The incidence of neonatal complications was 10.00 in the observation group and 66.67 in the control group, the difference was statistically significant (蠂 ~ 2 / 9.4810). Conclusion routine examination of pregnant women with syphilis infection can reduce the adverse outcome of pregnancy and reduce the incidence of congenital syphilis disease and complications.
【作者单位】：武汉市第一医院产科;
【基金】：湖北省科技厅科学技术基金资助项目(2013AB301C32)
【分类号】：R759.15

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