儿童泛发性光泽苔藓28例临床和病理特点分析

发布时间：2018-08-25 10:21

【摘要】：目的总结儿童泛发性光泽苔藓的临床和病理特点。方法回顾分析2014年1月-2015年12月北京儿童医院皮肤科门诊收治的28例儿童泛发性光泽苔藓患者的临床和病理资料。结果 28例患者中,27例(96.43%)为双侧对称分布,15例(53.57%)伴瘙痒,3例(10.71%)出现甲损害,5例(17.86%)见Koebner现象。28例行结核菌素纯蛋白衍生物试验(PPD)及11例行抗核抗体(ANA)检测,结果均为阴性。17例患儿组织病理示典型的表皮突下延呈"抱球样"环抱局限性浸润灶。4例(14.29%)患儿2年内皮疹自然消退,未给予任何治疗。结论儿童泛发性光泽苔藓为良性过程,暂未发现与结核感染和自身免疫性因素有相关性。
[Abstract]:Objective to summarize the clinical and pathological features of generalized lichen lustre in children. Methods the clinical and pathological data of 28 children with generalized lichen lustre were retrospectively analyzed from January 2014 to December 2015 in the dermatology department of Beijing Children's Hospital. Results among 28 patients, 27 cases (96.43%) had bilateral symmetrical distribution, 15 cases (53.57%) had bilateral symmetrical distribution, 3 cases (10.71%) had thyroid lesion, 5 cases (17.86%) had Koebner phenomenon. 28 cases were examined with tuberculin pure protein derivative test (PPD) and 11 cases with anti-nuclear antibody (ANA). Results the histopathological findings of 17 cases were negative. The histopathology of 17 cases showed that the typical infractory epidermis was "ball like". 4 cases (14.29%) had local infiltrating foci around the epidermis, and the rash subsided naturally within 2 years, and no treatment was given. Conclusion the generalized lichen lustre in children is a benign process and has not been found to be associated with tuberculosis infection and autoimmune factors.
【作者单位】：首都医科大学附属北京儿童医院皮肤科;首都医科大学附属北京儿童医院病理科;
【基金】：北京市医院管理局临床医学发展专项(ZYLX201601)
【分类号】：R758.69

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