皮肤纤维瘤38例临床与组织病理分析

发布时间：2018-09-17 13:05

【摘要】：目的探讨皮肤纤维瘤的临床与病理特点,提高皮肤科医生对本病的认识。方法回顾性分析2007年12月-2013年5月本院门诊收治的38例皮肤纤维瘤患者的临床和组织病理资料。结果皮肤纤维瘤患者中,男女比例为1∶2.2,平均发病年龄为(42.1±15.3)岁。14例(36.84%)患者皮损位于下肢,35例(92.11%)皮损单发。组织病理分型中以纤维型最为常见(28例,73.68%),其次为细胞型(8例,21.05%),血管瘤型最少见(2例,5.26%),肿瘤均位于真皮层,且多伴有表皮增生(31例,81.58%),并以银屑病样增生(14例,36.84%)和脂溢性角化病样增生(12例,31.58%)为主。结论皮肤纤维瘤好发于中年女性的下肢部位,皮损单发者多见,组织病理学分型中以纤维型更为常见,多伴有表皮银屑病样或脂溢性角化病样增生,将组织病理与临床表现相结合有助于本病的诊断。
[Abstract]:Objective to investigate the clinical and pathological features of cutaneous fibroma and to improve dermatologists' understanding of the disease. Methods the clinical and histopathological data of 38 patients with cutaneous fibroma treated in our hospital from December 2007 to May 2013 were retrospectively analyzed. Results the ratio of male to female was 1: 2.2, and the average age of onset was (42.1 卤15.3) years old (36.84%). 35 cases (92.11%) had skin lesions located in lower extremities. The most common histopathological types were fibrous type (28 cases, 73.68%), cell type (8 cases, 21.05%) and hemangioma type (2 cases, 5.26%). The tumors were located in the dermis. Most of them were associated with epidermis hyperplasia (31 cases, 81.58%), psoriatic hyperplasia (14 cases, 36.84%) and seborrheic keratosis (12 cases, 31.58%). Conclusion Dermatofibroma is more common in the lower extremities of middle aged women, and is more common in the histopathological classification with epidermal psoriasis or seborrheic keratosis. The combination of histopathology and clinical manifestations is helpful for the diagnosis of this disease.
【作者单位】：南通市第一人民医院皮肤科;
【分类号】：R739.5

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