中国人面部黑素细胞痣在皮肤镜下形态与年龄和面部部位的相关性研究

发布时间：2018-10-07 18:51

【摘要】：目的:探索中国人群面部黑素细胞痣(melanocytic nevus,MN)皮肤镜下常见的形态与年龄和面部部位的相关性。方法:用皮肤镜记录面部黑素细胞痣形态,以年龄层、部位进行分析比较。结果:假网状、球状、鹅卵石状、中央网状或均质状伴周围球状(mixed reticular/homogeneous nevi with peripheral globules,MP)、混合型的不同年龄层组间差异有统计学意义(P0.05),除鹅卵石状数量随年龄增长呈正相关性(P0.05),其余上述形态的数量随年龄增长均呈负相关性(P0.05)。各年龄层均以假网状最多;球状只出现在45岁组;鹅卵石状在16岁组才能观察到;MP及混合型只在30岁组。假网状、鹅卵石状、圈状在各部位分布差异有统计学意义(P0.05),上述形态在各部位比例高低如下,假网状:两颊口周额头鼻;鹅卵石状:两颊口周鼻子额头;圈状:两颊鼻部额头口周。首次提出圈状应为MN的形态之一。该研究未观察到中央球状或均质状伴周围网状(mix reticular nevi with central globules/homogeneous areas,MC)。结论:面部MN随年龄增长,假网状减少,球状及鹅卵石状总和增加,该研究可论证Nevogenisis的Abtropfung理论及内外源性途径。20岁有MP、MC、混合型特别是伴MN增大的患者应定期随访。鹅卵石状分布部位与Blaschko线基本符合;圈状与毛孔好发部位符合。
[Abstract]:Objective: to explore the relationship between age and facial site of facial melanocytic nevus (melanocytic nevus,MN) in Chinese population. Methods: the morphology of facial nevus of melanocytes was recorded by dermatoscope. Results: pseudo-reticular, globular, cobblestone, Central reticular or homogeneous with peripheral globular (mixed reticular/homogeneous nevi with peripheral globules,MP), there were significant differences among different age groups of mixed type (P0.05). The number of cobblestones was positively correlated with age (P0.05), and the number of other forms increased with age (P0.05). The length was negatively correlated (P0.05). False reticulation was the most common in all age groups; globular appearance was found only in 45 years old group; cobblestone was observed only in 16 years old group and mixed type was found only in 30 years old group. The distribution of pseudo-reticular, cobblestone and cobblestone was statistically significant (P0.05). The proportion of the above shape in each part was as follows: pseudo-reticular: frontal nose around two buccal orifice, cobblestone: nose forehead around buccal orifice; Circle-like: around the forehead and mouth of both cheeks and nostrils. For the first time, it was suggested that the ring shape should be one of the forms of MN. No central globular or homogeneous (mix reticular nevi with central globules/homogeneous areas,MC was observed in this study. Conclusion: facial MN increases with age, pseudo-reticular decrease, globular and cobblestone summation. This study can demonstrate the Abtropfung theory of Nevogenisis and the internal and external pathway. 20 years old patients with mixed MP,MC, especially with increased MN, should be followed up regularly. The distribution of cobblestone was basically consistent with Blaschko line, and that of circle and pore was consistent.
【作者单位】：厦门长庚医院皮肤科;上海复旦大学附属华山医院皮肤科;
【分类号】：R758.51

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