肛门、直肠梅毒5例临床病理分析

发布时间：2018-11-17 08:28

【摘要】：目的分析肛门直肠梅毒的临床及组织病理学特点,提高临床及病理医生对梅毒的认识,避免漏诊、误诊。方法回顾性分析5例肛门直肠梅毒的临床及组织病理学形态,结合实验室资料进行诊断,并分析误诊原因。结果患者均为男性,均有不洁性生活史。其中一期梅毒1例,二期3例,三期1例,初诊时临床、病理均漏诊。组织病理学特点:肛周皮肤、肛管、直肠黏膜的表面轻度糜烂,大量中性粒细胞浸润,微脓肿形成;鳞状上皮假上皮瘤样增生,棘层增厚,上皮脚下延,表皮细胞内及细胞间水肿,真皮层大量浆细胞及淋巴细胞浸润,血管周围尤为显著。结论肛门、直肠梅毒临床少见,临床和病理医生容易漏诊、误诊。掌握梅毒的临床特点和组织病理形态学特征,提高对梅毒的认识。
[Abstract]:Objective to analyze the clinical and histopathological features of anorectal syphilis, to improve the understanding of syphilis among clinicians and pathologists, to avoid missed diagnosis and misdiagnosis. Methods the clinical and histopathological features of 5 cases of anorectal syphilis were analyzed retrospectively. Results all the patients were male and had a history of unclean sexual life. There were 1 case of primary syphilis, 3 cases of secondary syphilis and 1 case of stage 3 syphilis. Histopathological features: perianal skin, anal canal, rectal mucosa surface mild erosion, a large number of neutrophils infiltration, microabscess formation; Squamous epithelial pseudoepithelioma hyperplasia, thickening of spinous layer, extension of epithelium, edema in epidermal cells and between cells, infiltration of plasma cells and lymphocytes in dermis, especially around blood vessels. Conclusion anal and rectal syphilis is rare in clinic, and it is easy to be missed and misdiagnosed by clinicians and pathologists. To grasp the clinical and histopathologic features of syphilis and improve the understanding of syphilis.
【作者单位】：青海红十字医院病理科;
【分类号】：R759.1

【参考文献】