小汗腺汗孔癌5例临床表现及组织病理分析
发布时间:2018-11-18 10:51
【摘要】:目的了解小汗腺汗孔癌的临床特征及组织病理特点。方法对第四军医大学西京皮肤医院2007年4月-2015年8月经组织病理学检查确诊的5例小汗腺汗孔癌患者的临床及组织病理特点进行回顾性分析。结果 5例小汗腺汗孔癌患者中,男3例,女2例,平均年龄66.8岁,中位年龄69岁,平均病程1.5年。皮损部位:鼻部1例,颞部1例,下肢3例。临床表现多为结节及斑块,多数皮损伴有不同程度瘙痒、疼痛、糜烂及破溃。皮损组织病理可见排列紧密的团块状嗜伊红鳞状样细胞或基底样细胞,分布不典型,团块中央可见导管分化结构,细胞异型性明显。结论该病临床表现无明显特异性,确诊需要依靠组织病理检查。治疗上应早期予以手术切除皮损。若无转移病灶则预后较好。
[Abstract]:Objective to investigate the clinical and histopathological features of eccrine sweat pore carcinoma. Methods the clinical and histopathological features of 5 patients with eccrine sweat pore carcinoma diagnosed by histopathological examination from April 2007 to August 2015 in Xijing skin Hospital of fourth military Medical University were retrospectively analyzed. Results among the 5 patients, there were 3 males and 2 females, with an average age of 66.8 years and a median age of 69 years, with an average course of 1.5 years. The lesions were nasal in 1 case, temporal in 1 case and lower extremity in 3 cases. Most of the lesions were associated with itching, pain, erosion and ulceration. Histopathology of lesions showed that there were dense clusters of eosinophilic squamous cells or basal cells with atypical distribution. The differentiation structure of ducts was seen in the center of the lumps and the heterogeneity of the cells was obvious. Conclusion there is no obvious specificity in clinical manifestation of the disease, and the diagnosis depends on histopathological examination. Early surgical excision of skin lesions should be performed on the treatment. If there were no metastatic lesions, the prognosis was better.
【作者单位】: 第四军医大学西京皮肤医院;
【分类号】:R739.5
[Abstract]:Objective to investigate the clinical and histopathological features of eccrine sweat pore carcinoma. Methods the clinical and histopathological features of 5 patients with eccrine sweat pore carcinoma diagnosed by histopathological examination from April 2007 to August 2015 in Xijing skin Hospital of fourth military Medical University were retrospectively analyzed. Results among the 5 patients, there were 3 males and 2 females, with an average age of 66.8 years and a median age of 69 years, with an average course of 1.5 years. The lesions were nasal in 1 case, temporal in 1 case and lower extremity in 3 cases. Most of the lesions were associated with itching, pain, erosion and ulceration. Histopathology of lesions showed that there were dense clusters of eosinophilic squamous cells or basal cells with atypical distribution. The differentiation structure of ducts was seen in the center of the lumps and the heterogeneity of the cells was obvious. Conclusion there is no obvious specificity in clinical manifestation of the disease, and the diagnosis depends on histopathological examination. Early surgical excision of skin lesions should be performed on the treatment. If there were no metastatic lesions, the prognosis was better.
【作者单位】: 第四军医大学西京皮肤医院;
【分类号】:R739.5
【参考文献】
相关期刊论文 前3条
1 吴亚桐;常建民;;小汗腺汗孔癌[J];临床皮肤科杂志;2014年04期
2 赵菊平;祝宇;何z殉,
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