毫火针联合窄谱中波紫外线治疗白癜风的疗效观察

发布时间：2018-11-21 14:12

【摘要】：目的:比较毫火针与窄谱中波紫外线(NB-UVB)联合、单用毫火针、单用NB-UVB治疗稳定期局限型白癜风的疗效。方法:将稳定期局限型白癜风患者77例随机分为3组。3组均服用复合维生素B片。治疗组31例,予毫火针联合NB-UVB治疗;对照1组23例,予毫火针治疗;对照2组23例,予NB-UVB治疗。疗程16周。于治疗第4周末、第8周末、第12周末、第16周末观察疗效、记录不良反应。并于第16周末用Wood灯对临床痊愈的皮损进行检查。结果:第16周末,治疗组总有效率83.87%,愈显率64.51%;对照1组总有效率73.91%,愈显率52.17%;对照2组总有效率52.17%,愈显率21.74%。治疗组与对照1组比较,总有效例数和愈显例数差异无统计学意义(P0.05)。治疗组与对照2组比较,总有效例数和愈显例数差异统有计学意义(P0.05)。对照1组与对照2组比较,总有效例数差异无统计学意义(P0.05),愈显例数差异统有计学意义(P0.05)。结论:对于稳定期局限型白癜风,毫火针联合NBUVB疗法具有较好的疗效和安全性,其疗效优于NB-UVB疗法,但与毫火针无统计学差异。
[Abstract]:Objective: to compare the efficacy of neutrophilic needle combined with narrow band ultraviolet B (NB-UVB) alone and NB-UVB in the treatment of stable localized vitiligo. Methods: 77 patients with stable localized vitiligo were randomly divided into 3 groups. 31 cases in the treatment group were treated with NB-UVB, 23 cases in the control group, 23 cases in the control group, and 23 cases in the control group were treated with NB-UVB. The course of treatment was 16 weeks. The therapeutic effects were observed at the end of the 4th, 8th, 12th and 16th weeks. Adverse reactions were recorded. At the end of the 16 th week, Wood lamp was used to check the cured skin lesions. Results: at the end of the 16th week, the total effective rate in the treatment group was 83.87, the more obvious rate was 64.51, the total effective rate in the control group was 73.91, the more obvious rate was 52.17.The total effective rate in the control group was 52.17 and the more obvious rate was 21.74. There was no significant difference in the total effective cases and the number of callus cases between the treatment group and the control group (P0.05). Compared with the control group, the difference between the total effective cases and the more obvious cases was statistically significant (P0.05). There was no significant difference in the total effective cases between the control group 1 and the control group (P0.05), but the difference in the number of the more obvious cases was statistically significant (P0.05). Conclusion: for stable localized vitiligo, the combination of NBUVB and Needle has better curative effect and safety than NB-UVB, but there is no statistical difference between them.
【作者单位】：南方医科大学附属小榄医院;
【分类号】：R758.41

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