获得性反应性穿通性胶原病7例临床分析并文献复习
发布时间：2018-12-29 16:52
【摘要】：目的:探讨获得性反应性穿通性胶原病(ARPC)的临床表现、发病机制和组织病理特点。方法:回顾性分析7例ARPC患者的临床资料,同时复习国内外文献。结果:7例患者中男5例,女2例,年龄50~67岁。其中3例患者有基础疾病,4例患者在随访中复发,1例出现肿瘤指标异常。7例患者皮损Kobner现象均阳性,且皮损组织病理表现相似。结论:ARPC临床表现大多无特异性,需结合病史和组织病理检查明确诊断,目前尚无统一的治疗方案,减轻瘙痒是治疗的关键因素之一,该病的复发可能与患者是否存在系统性疾病有关。
[Abstract]:Objective: to investigate the clinical manifestations, pathogenesis and histopathological features of acquired reactive penetrating collagenosis (ARPC). Methods: the clinical data of 7 patients with ARPC were retrospectively analyzed and the literature at home and abroad were reviewed. Results: there were 5 males and 2 females aged 50 to 67 years. Among them, 3 patients had basic diseases, 4 patients had recurrence during follow-up, 1 patient had abnormal tumor index, 7 patients had positive Kobner phenomenon in skin lesions, and the histopathological manifestations of skin lesions were similar. Conclusion: most of the clinical manifestations of ARPC are nonspecific, so it is necessary to make a definite diagnosis in combination with the history and histopathological examination. There is no unified treatment plan at present. Reducing pruritus is one of the key factors in the treatment. The recurrence of the disease may be related to the existence of systemic disease.
【作者单位】： 上海市皮肤病医院中西医结合皮肤科;
【分类号】：R758.6
本文编号：2395092
[Abstract]:Objective: to investigate the clinical manifestations, pathogenesis and histopathological features of acquired reactive penetrating collagenosis (ARPC). Methods: the clinical data of 7 patients with ARPC were retrospectively analyzed and the literature at home and abroad were reviewed. Results: there were 5 males and 2 females aged 50 to 67 years. Among them, 3 patients had basic diseases, 4 patients had recurrence during follow-up, 1 patient had abnormal tumor index, 7 patients had positive Kobner phenomenon in skin lesions, and the histopathological manifestations of skin lesions were similar. Conclusion: most of the clinical manifestations of ARPC are nonspecific, so it is necessary to make a definite diagnosis in combination with the history and histopathological examination. There is no unified treatment plan at present. Reducing pruritus is one of the key factors in the treatment. The recurrence of the disease may be related to the existence of systemic disease.
【作者单位】： 上海市皮肤病医院中西医结合皮肤科;
【分类号】：R758.6
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