克廷肤治疗儿童湿疹疗效观察

发布时间：2019-04-08 13:01

【摘要】：背景:儿童湿疹是湿疹类型中的一种,同成人湿疹本质上没有区别,症状常伴有轻重不一的瘙痒,皮疹可发生于身体的任何部位,多对称发生于身体两侧,通常按其病程和临床特点可分为急性、亚急性和慢性湿疹。关于0.05%丙酸氟替卡松乳膏(克廷肤)治疗儿童湿疹的国内相关报道较少。目的:观察克廷肤治疗儿童湿疹疗效和安全分析。方法:搜集门诊患者148例,随机分为克廷肤组和艾洛松组2组,分别使用克廷肤和艾洛松治疗观察,疗程2周,然后根据各项治疗指标进行比较。结果:克廷肤组治疗1周后、2周后的有效率明显高于艾洛松组,并且两组之间差异有统计学意义(克廷肤组1周后有效率为80.3%,艾洛松组1周后有效率为55.7%,X~2 =10.415,P=0.0010.05;克廷肤组2周后有效率为90.8%,艾洛松组2周后有效率为70.8%,X~2 =9.599,P=0.0020.05). 结论:克廷肤治疗儿童湿疹疗效高,安全性好。
[Abstract]:Background: eczema in children is one of the types of eczema that is essentially no different from adult eczema. Symptoms are often accompanied by itching of varying severity. Rashes can occur in any part of the body and more symmetrically on both sides of the body. Usually according to the course of disease and clinical characteristics can be divided into acute, subacute and chronic eczema. There are few reports on the treatment of eczema in children with 0.05% fluticasone propionate cream. Objective: to observe the efficacy and safety of Curtin skin in the treatment of eczema in children. Methods: 148 outpatients were randomly divided into two groups: Ketinskin group and Eloxone group. The patients were treated with ketinskin and Eloxone for 2 weeks, and then compared according to the indexes of treatment. Results: the effective rate after 1 week treatment and 2 weeks after treatment in the Ketinfu group was significantly higher than that in the Eloxone group, and there was a significant difference between the two groups (80.3% after one week in the Ketingfu group and 55.7% in the Eloxone group after 1 week treatment), and the effective rate in the two groups was significantly higher than that in the Eloxone group. X _ (2) = 10.41 ~ (15), P _ (x) 0.0010.05; The effective rate was 90.8% in the Ketingfu group and 70.8% in the Eloxone group 2 weeks later, and the effective rate was 9.599, P = 0.0020.05 in the clotin skin group and in the Eloxone group after 2 weeks. Conclusion: Keating skin is effective and safe in the treatment of eczema in children.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R758.23

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