中药面膜联合果酸治疗寻常性痤疮的临床研究

发布时间：2019-04-19 19:59

【摘要】：目的：通过观察中药面膜联合果酸对寻常性痤疮皮损的数量、类型、颜色、肿痛、皮肤油脂含量、皮肤含水量的影响，以探讨其临床疗效及作用机制，，为痤疮的临床治疗提供一种简单易行，安全有效的方法。方法：将110例寻常性痤疮患者随机分为治疗组和对照组。治疗组给予中药面膜加果酸治疗，果酸治疗每4周一次，每次果酸治疗一周后给予中药面膜治疗，每周2次，连续3周中药面膜。对照组给予果酸治疗，果酸治疗每4周一次。观察两组皮损的变化情况（皮损数量、类型、颜色、肿痛），并记录其积分变化。并用COURAGE KHAZAKA公司（CK公司）多功能皮肤检测仪对患者面部皮肤的油脂含量、含水量进行检测。总疗程为3个月，疗程结束后判定疗效。结果：101例患者完成治疗。治疗组总有效率98.08％，治愈率和显效率达90.38％，痊愈率28.85％，对照组总有效率93.88％，治愈率和显效率达48.98％，痊愈率8.16％。两组总有效率比较差异无统计学意义（P＞0.05），两组治愈率显效率之和比较差异有统计学意义（P＜0.01），两组痊愈率比较差异有统计学意义（P＜0.05）。两组治疗后皮肤油脂含量较治疗前减少，通过统计学比较有显著差异（P＜0.01）。两组治疗后角质层含水量较治疗前增加，通过统计学比较有显著统计学意义（P＜0.01）。治疗后两组皮肤油脂含量、角质层含水量比较有显著统计学意义（P＜0.01）。结论：中药面膜联合果酸治疗寻常性痤疮的临床疗效优于单纯果酸治疗,能减少痤疮皮肤的油脂含量，提高角质层的水分含量，恢复皮肤屏障功能。该方法可作为治疗寻常性痤疮的一种安全有效的手段，值得在临床上进一步推广。
[Abstract]:Objective: to observe the effect of traditional Chinese medicine mask combined with pectic acid on the quantity, type, color, swelling and pain of acne vulgaris, the content of oil in skin and the water content of skin, so as to explore the clinical curative effect and the mechanism of action. To provide a simple, safe and effective method for the clinical treatment of acne. Methods: 110 patients with acne vulgaris were randomly divided into treatment group and control group. The patients in the treatment group were treated with traditional Chinese medicine mask and pectic acid every 4 weeks. After one week of treatment, they were treated with the Chinese medicine mask twice a week for 3 weeks. The patients in the treatment group were treated with traditional Chinese medicine facial mask twice a week for 3 weeks. The control group was treated with fruit acid, and the fruit acid treatment was given every 4 weeks. Observe the changes of the lesions (quantity, type, color, swelling and pain) of the two groups and record their integral changes. COURAGE KHAZAKA company (CK company) multi-function skin detector was used to detect the oil content and water content of the patient's facial skin. The total course of treatment was 3 months, and the curative effect was determined after the end of the course. Results: 101 patients completed treatment. The total effective rate of the treatment group was 98.08%, the cure rate and remarkable rate was 90.38%, the cure rate was 28.85%, the total effective rate was 93.88% in the control group, the cure rate and remarkable efficiency was 48.98%, and the cure rate was 8.16%. There was no significant difference in the total effective rate between the two groups (P > 0.05). There was a significant difference in the sum of cure rate between the two groups (P < 0.01), and there was a significant difference in the cure rate between the two groups (P < 0.05). After treatment, the skin fat content in the two groups was lower than that before treatment, and there was a significant difference between the two groups (P < 0.01). After treatment, the water content of the cuticle in the two groups was higher than that before treatment, and there was a significant statistical difference between the two groups (P < 0.01). After treatment, there was significant difference in the content of skin fat and the water content of cuticle between the two groups (P < 0.01). Conclusion: the clinical efficacy of traditional Chinese medicine facial mask combined with pectic acid in treating acne vulgaris is better than that of simple pectic acid treatment. It can reduce the oil content of acne skin, increase the moisture content of cuticle, and restore the skin barrier function. This method can be used as a safe and effective method in the treatment of acne vulgaris.
【学位授予单位】：泸州医学院
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R758.733

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