血脂水平与动脉瘤性蛛网膜下腔出血后迟发性脑缺血的相关性

发布时间：2017-12-26 19:20

  本文关键词：血脂水平与动脉瘤性蛛网膜下腔出血后迟发性脑缺血的相关性　出处：《中国临床神经外科杂志》2016年11期 　论文类型：期刊论文

  更多相关文章： 动脉瘤性蛛网膜下腔出血 迟发性脑缺血 血脂 改良Fisher分级

【摘要】：目的探讨血脂水平与动脉瘤性蛛网膜下腔出血(a SAH)后迟发性脑缺血(DCI)的相关性。方法回顾性分析2014年1月至2015年12月收治的74例a SAH的临床资料,采用多因素Logistic回归分析检验性别、年龄、动脉瘤位置、动脉瘤大小、世界神经外科医师联盟(WFNS)分级、改良Fisher分级、Hunt-Hess分级、治疗方式、总甘油三脂、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、脂蛋白(a)、载脂蛋白A、载脂蛋白B等因素与DCI的关系。结果 74例中,65例入院后检测血脂,20例出现DCI,45例未出现DCI,a SAH后DCI的发生率为30.8%。多因素Logistic回归分析显示高甘油三酯及改良Fisher分级是a SAH后DCI发生的独立危险因素。结论及时检测a SAH患者的血脂水平和对患者进行改良Fisher分级对DCI的诊断治疗均有参考价值。
[Abstract]:Objective to investigate the correlation between blood lipid level and delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (a SAH). Methods Retrospective analysis of clinical data from January 2014 to December 2015 were 74 cases of a SAH, multivariate Logistic regression analysis was used to test gender and age, aneurysm location, aneurysm size, the world alliance of neurosurgeons (WFNS) grade, modified Fisher grade, Hunt-Hess grade, treatment, total glycerin three fat, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, lipoprotein (a), the relationship between DCI factor and apolipoprotein A, apolipoprotein B etc.. Results of the 74 cases, 65 cases were tested for blood lipid, 20 cases had DCI, 45 cases had no DCI, and the incidence of DCI after a SAH was 30.8%. Multifactor Logistic regression analysis showed that high triglyceride and improved Fisher classification were independent risk factors for DCI after a SAH. Conclusion the timely detection of blood lipid levels in a SAH patients and the improved Fisher classification for patients are of reference value for the diagnosis and treatment of DCI.
【作者单位】： 石河子大学医学院第一附属医院神经外科;
【基金】：国家科技支撑计划(2013BAI05B05)
【分类号】：R743.35
【正文快照】： 蛛网膜下腔出血(subrachnoid hemorrhage,SAH)指脑底部或脑表面的病变血管破裂,血液直接流入蛛网膜下腔引起的一种临床综合征,是临床常见的脑血管疾病,主要原因是颅内动脉瘤破裂出血。动脉瘤性SAH(aneurysamal SAH,a SAH)致残率、病死率均较高,与迟发性脑缺血(delayed cerebra，

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