丙戊酸联合拉莫三嗪治疗癫痫的临床效果分析

发布时间：2017-12-26 21:32

本文关键词：丙戊酸联合拉莫三嗪治疗癫痫的临床效果分析　出处：《世界最新医学信息文摘》2016年62期 　论文类型：期刊论文

【摘要】：目的探讨丙戊酸联合拉莫三嗪治疗癫痫的临床效果。方法选取我院2013年5月至2016年4月中收治的26例癫痫患者作为本次实验的研究对象,并按照药物治疗的差异,将参与实验的患者分为两个不同的小组,分别将其定义为研究组(n=13例),与对照组(n=13例),对照组患者采取丙戊酸进行治疗,研究组则在其基础上接受拉莫三嗪的治疗,治疗完成后,对两个小组的临床疗效进行分析。结果通过比较得知,研究组患者在3月、6月以及1年后的发病频率均明显低于对照组患者,临床疗效明显优于对照组患者,数据差异具有统计学意义(P0.05)。治疗完成后,研究组患者的总有效率与对照组患者相比,具有明显的优势,数据差异具有统计学意义(P0.05)。结论丙戊酸联合拉莫三嗪治疗癫痫的临床效果比较明显,可明显降低患者癫痫发作的频率,对其生活质量的改善有着积极的意义,值得推广。
[Abstract]:Objective to investigate the clinical effect of valproate and lamotrigine in the treatment of epilepsy. Methods 26 patients with epilepsy in our hospital from May 2013 to 2016 4 months were treated as the research object of this experiment, and according to the difference of drug treatment, will participate in the experiment were divided into two groups, respectively, which is defined as the study group (n=13 cases), and control group (n=13 cases), the control group of patients taking valproate treatment, treatment study group received lamotrigine on the basis, after completion of therapy, the clinical curative effects of two groups were analyzed. Results by comparison, we found that the incidence of patients in the study group in March, June and 1 years were significantly lower than those in the control group, the clinical efficacy was significantly better than that in the control group, and the data difference was statistically significant (P0.05). After the treatment was completed, the total effective rate of the patients in the study group was significantly superior to those in the control group, and the difference of the data was statistically significant (P0.05). Conclusion the clinical effect of valproic acid combined with lamotrigine in the treatment of epilepsy is more obvious, can significantly reduce the seizure frequency, has a positive significance to the improvement of the quality of life, worthy of promotion.
【作者单位】：河南省郑州市中牟县第二人民医院;
【分类号】：R742.1
【正文快照】： 癫痫是临床上常见的一种神经系统病变[1],为进一步对其治疗方案进行探讨,笔者选取我院2013年5月至2016年4月中收治的26例癫痫患者,并对其中13例患者采取了丙戊酸以及拉莫三嗪联合治疗的方式,取得了良好的临床疗效,现将具体的报告如下呈现:1资料与方法1.1一般资料选取我院2013

【参考文献】