初发脑卒中后抑郁各时期的患病情况及相关因素分析

发布时间：2017-12-27 01:27

本文关键词：初发脑卒中后抑郁各时期的患病情况及相关因素分析　出处：《中华全科医学》2016年06期 　论文类型：期刊论文

【摘要】：目的分析初发脑卒中后抑郁(PSD)各时期患病情况及相关因素。方法选择嘉兴市第二医院收治的64例初发脑卒中患者,分别在入院1、3、6及12个月时应用汉密尔顿抑郁量表(HAMD)、日常生活能力评定量表(ADL)、社会支持评定量表(SSRS)、神经功能缺损程度评分量表及艾森克人格问卷简式量表中国版(EPQ-RSC)对患者进行评定,统计PSD在各时间点发病率及相关因素分析。结果卒中后抑郁在1、3、6、12个月时PSD的发病率分别为18.75%、29.03%、37.70%、31.03%;卒中后1、3、6个月时PSD者女性及内向性格占比均显著高于非PSD者(P0.05),且卒中后3、6、12个月时PSD者日常生活能力评分、社会支持评分显著低于非PSD者,而神经功能缺损评分显著高于非PSD者,比较差异均有统计学意义(P0.05);对各高危因素进行Logistic回归性分析显示卒中后1个月时PSD的发生率与内向性格及女性有关联性(P0.05);3个月时PSD的发生与女性、日常生活能力、社会支持及神经功能缺损有关(P0.05);6个月及12个月时,PSD的发生与日常生活能力、社会支持及神经功能缺损有关(P0.05)。结论对于脑卒中患者而言,抑郁的发病率较高,在临床诊疗中,早期应密切关注女性、性格内向者,中、晚期应加强对低水平日常生活能力者及社会支持者和伴有严重神经功能缺损者的监护,提前预防,尽早治疗,以降低本病发生率。
[Abstract]:Objective to analyze the prevalence and related factors of the early post stroke depression (PSD). Methods 64 patients admitted to Jiaxing Second Hospital of primary stroke patients, respectively 1, 3, 6 at admission and 12 months with Hamilton Depression Scale (HAMD), daily life ability scale (ADL), social support rating scale (SSRS), neurological impairment rating scale and Eysenck personality questionnaire China Version (EPQ-RSC) were used to evaluate and analysis the incidence and relevant factors in each time point PSD statistics. The incidence of depression after stroke in 1, 3, 6, 12 month PSD rates were 18.75%, 29.03%, 37.70%, 31.03%; 1, 3 and 6 months after stroke and PSD female introversion ratio were significantly higher than those of non PSD (P0.05), ability of daily life and 3 after stroke 6, and 12 months PSD score and social support score was significantly lower than that in non PSD group, and the neurological deficit score was significantly higher than that of non PSD, the differences were statistically significant (P0.05); the risk factors Logistic regression analysis showed that stroke at 1 months after the occurrence of PSD and introverted personality and Women Association (P0.05); 3 months for women, PSD and the ability of daily life, social support and neurological deficit (P0.05); 6 and 12 months, the incidence of PSD is related to the ability of daily life, social support and neurological deficit (P0.05). Conclusion for the patients with stroke, the incidence of depression is higher in the clinical diagnosis and treatment, early should pay close attention to women, introvert, middle and late low level should strengthen the ability of daily life care of neurological defects and social support and with the early prevention, early treatment, in order to reduce the incidence of this disease.
【作者单位】：嘉兴市第二医院神经内科;嘉兴市第二医院精神科;
【基金】：浙江省中医药科学研究基金计划项目(2010ZB147) 2015年浙江省嘉兴市科技局计划项目(2015AY-23021)
【分类号】：R743.3
【正文快照】： 随着现今生活方式和饮食结构的改变,脑卒中发病率呈现逐年递增趋势,脑卒中抑郁是脑卒中后临床中最常见的并发症之一,有研究认为其发病率约占卒中患者的40%~50%,多发生于卒中后的2个月~1年[1-2]。因本病发生之后具有较强的隐蔽性,加之有些卒中患者语言存在障碍等,不能较好地与

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