校正后中文版神经病理性疼痛量表的多中心验证

发布时间：2017-12-31 12:09

本文关键词：校正后中文版神经病理性疼痛量表的多中心验证　出处：《中国疼痛医学杂志》2016年03期 　论文类型：期刊论文

【摘要】：目的:验证中文版神经病理性疼痛量表(Neuropathic Pain Questionnaire,NPQ)。方法:三个研究中心共入选神经病理性疼痛患者60例,伤害感受性疼痛患者60例。入选的患者自行填写中文版NPQ,必要时由经培训的研究人员为患者解释量表中的问题。使用Cronbach’s Alpha系数和Guttman分半系数评价中文版NPQ的信度。使用ROC曲线下面积、敏感度、特异度、阳性预测值和阴性预测值评价量表的内容效度。结果:入组120例患者,其中男47例,女73例。中文版NPQ量表的信度好(Cronbach’s Alpha系数为0.838,Guttman分半系数为0.818);中文版NPQ的内容效度好(ROC曲线下面积为0.985,敏感度为88.3%,特异度为98.3%,阳性预测值为98.1%,阴性预测值为89.4%)。结论:中文为母语的患者可以使用本研究验证的中文版NPQ作为神经病理性疼痛的诊断工具。
[Abstract]:Objective: to verify the Chinese version of the neuropathic pain scale (Neuropathic Pain Questionnaire, NPQ). Methods: three patients were enrolled in a research center of neuropathic pain in 60 cases, nociceptive pain in 60 patients. The patients to choose the Chinese version of NPQ, if necessary, by researchers trained to explain scale problems in patients using Cronbach 's Alpha coefficient and Guttman coefficient to evaluate the reliability of semi Chinese divided version of NPQ. The use of the area under ROC curve, sensitivity, specificity, positive predictive value and negative predictive value of content validity evaluation scale. Results: 120 patients were enrolled, including 47 male cases, 73 female cases Chinese version. NPQ scale reliability is good (Cronbach' s Alpha coefficient is 0.838, Guttman split half coefficient is 0.818); Chinese version of NPQ good content validity (ROC area under curve was 0.985, sensitivity was 88.3%, specificity was 98.3%, the positive predictive value was 98.1%, negative The predictive value is 89.4%). Conclusion: Chinese language patients can be used as a diagnostic tool for neuropathic pain using the Chinese version of NPQ, which is verified by this study.

【作者单位】：北京大学人民医院疼痛医学科;南京军区南京总医院麻醉科疼痛医学中心;中日友好医院疼痛科;
【基金】：辉瑞制药有限公司研究者发起研究基金(IIR基金)WS538356
【分类号】：R741
【正文快照】： 神经病理性疼痛作为一种独立的疼痛分类,在发病机制、临床表现等方面都不同于伤害感受性疼痛,药物治疗也有很大差别。英国的一项调查显示普通人群中神经病理性疼痛的患病率为8%[1],神经病理性疼痛由于疼痛强度大、持续时间长、花费多,造成的经济负担也较重[2],早期、正确诊断

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