氯吡格雷与阿司匹林联合口服治疗急性进展性侧脑室旁脑梗死的临床观察

发布时间：2018-01-20 19:20

本文关键词： 氯吡格雷阿司匹林联合脑梗死疗效　出处：《临床医药文献电子杂志》2016年51期 　论文类型：期刊论文

【摘要】：目的分析讨论联合口服氯吡格雷与阿司匹林在治疗急性进展性侧脑室旁脑梗死中的疗效。方法选取我院神经内科2014年1月~2015年12月收治的急性进展性侧脑室旁脑梗死患者40例作为研究对象,将其随机分为观察组和对照组,各20例。对照组采取口服阿司匹林治疗方法,观察组采取氯吡格雷联合阿司匹林口服治疗方法,观察并分析两组的疗效以及不良反应情况。结果观察组治疗后3天、7天、30天、90天的NIHSS评分以及Barthel指数评分均明显优于对照组,差异均有统计学意义(P0.05);两组患者的不良反应发生率比较,差异无统计学意义(P0.05)。结论联合口服氯吡格雷与阿司匹林治疗急性进展性侧脑室旁脑梗死,可获得显著的疗效,可有效阻断脑梗死进展的过程,防止病情的加重。
[Abstract]:Objective to evaluate the efficacy of clopidogrel combined with aspirin in the treatment of acute progressive paraventricular infarction. Forty patients with progressive paraventricular infarction were studied. It was randomly divided into the observation group and the control group, 20 cases each. The control group was treated with oral aspirin, and the observation group with clopidogrel combined with oral aspirin. Results the NIHSS scores and Barthel index scores in the observation group were significantly better than those in the control group in 3 days, 7 days and 30 days and 90 days after treatment. The difference was statistically significant (P 0.05). There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion the combination of clopidogrel and aspirin in the treatment of acute progressive paraventricular infarction can obtain significant curative effect. Can effectively block the progress of cerebral infarction process, prevent the aggravation of the disease.
【作者单位】：海门市中医院神经内科;
【分类号】：R743.33
【正文快照】： 进展性脑梗死是急性脑梗死中常见且严重的临床亚型,约占全部脑梗死的26%~43%,它的临床特点是发病后局限性脑缺血、神经功能缺失症呈逐渐加重趋势[1],可持续6 h至数天以上,若得不到及时有效的治疗措施或者治疗不当,会引起不可逆的神经功能缺损症状,最终导致完全性脑梗死,且该病

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