中国北方城市气象和污染因素对不同脑卒中亚型的影响

发布时间：2018-01-23 19:46

本文关键词： 脑卒中 PM_(.) 短暂性脑缺血发作蛛网膜下腔出血　出处：《广东医学》2017年16期 　论文类型：期刊论文

【摘要】：目的探讨各种气象和污染指标对不同脑卒中亚型的影响。方法收集2年每月脑卒中发病人数。研究对象分成两类:缺血性脑血管病和出血性脑血管病,再将疾病分成各个亚型。从中国环保部收集研究期间24 h空气污染颗粒直径小于2.5μm(PM_(2.5))和24 h最高NO_2这两种空气污染数据,以及气象指标每月平均温度、平均湿度和温度日较差。使用泊松线性回归模型来研究脑卒中亚型和天气、空气污染物的关系。结果短暂性脑缺血发作与平均气温呈负相关(RR=0.989,95%CI 0.996~0.981,P=0.003),并且与平均温度日较差(RR=1.296,95%CI 1.357~1.238,P=0.000)和PM_(2.5)(RR=1.109,95%CI 1.135~1.084,P=0.000)关系最大,而蛛网膜下腔出血则与平均湿度(RR=0.942,95%CI 0.987~0.899,P=0.012)和NO_2(RR=0.873,95%CI 0.994~0.767,P=0.041)呈负相关。结论平均气温、平均温度日较差和PM_(2.5)对短暂性脑缺血发作的影响较大,而平均湿度、NO_2对蛛网膜下腔出血的影响较明显。
[Abstract]:Objective to investigate the effects of meteorological and pollution indexes on different types of cerebral apoplexy. Methods the number of stroke cases per month for 2 years was collected. The subjects were divided into two categories: ischemic cerebrovascular disease and hemorrhagic cerebrovascular disease. The disease was subdivided into subtypes. The air pollution particles were less than 2.5 渭 m in diameter during the 24 h study from the Ministry of Environmental Protection of China. And 24 h maximum NO_2 data. And the mean monthly temperature, average humidity and daily temperature range of meteorological indicators. The Poisson linear regression model was used to study the subtype and weather of cerebral apoplexy. Results there was a negative correlation between transient ischemic attack and mean air temperature. And with the average daily temperature range RRX 1.296 ~ 95CI 1.3571.238P0. 000) and PM_(2.5)(RR=1.109. 95 CI 1.135 ~ 1.084% (P = 0.000), while subarachnoid hemorrhage was associated with mean humidity (RRN) 0.942. 95 CI 0.987 + 0.899P0. 012) and no _ 2 / R _ (0.873 / 95 CI 0.994 / 0.767). Conclusion mean air temperature, mean daily temperature range and PMs2. 5) have a great effect on transient ischemic attack, but mean humidity. The effect of NO_2 on subarachnoid hemorrhage was obvious.
【作者单位】：南方医科大学第一临床医学院;广州医科大学附属第二医院胃肠外科;广东省第二人民医院生殖医学中心;南方医科大学公共卫生学院;南方医科大学南方医院风湿免疫科;泰达国际心血管病医院基础医学研究中心;哈尔滨医科大学附属第二医院神经内科;
【分类号】：R743.3
【正文快照】： 脑卒中是全世界致死和致残的重要原因。在2015年,仅在中国就影响了近7千万人,占将近5%的人口。其中包括270万的新发脑卒中和160万的脑卒中死亡病例。随着空气污染日趋严重,空气污染对人体健康的影响也越来越受到重视。近年来,陆续有文献报道[1-2]天气因素以及污染物对脑卒中发

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