血流动力学改变与后交通动脉瘤形成的相关性分析

发布时间：2018-01-26 09:48

本文关键词： 血流动力学后交通动脉瘤数字减影血管造影　出处：《大连医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的：探讨后交通动脉变异及颈内动脉C1、C2段夹角情况引起的血流动力学改变与后交通动脉瘤形成的相关性。方法：本研究选取2008年1月至2013年12月期间于大连医科大学附属第二医院神经内科就诊的且明确诊断为后交通动脉瘤的76例患者，随机抽选同期住院的非颅内动脉瘤患者78例，上述患者均行脑血管造影术检查，其全脑血管造影资料及其他一般病史情况全部收集齐全。按照大脑后动脉供血类型的不同将后交通动脉分为三型：PO型、PI型及PII型。分别统计动脉瘤组及对照组三种类型后交通动脉的血管数，与对照组（非动脉瘤组）进行比较分析。同时统计动脉瘤组中三种后交通动脉类型各自发生动脉瘤的情况，三者行两两比较。根据脑血管造影片，对后交通动脉瘤患侧及对侧的颈内动脉C1段、C2段夹角(即后交通动脉多发处附近)进行测量，并与对照组(非动脉瘤组)进行比较分析。应用统计学软件SPSS17.0进行数据分析，计数资料采用卡方检验，计量资料采用t检验，P0.05表明差异有统计学意义，P0.01表明具有显著统计学差异。结果： 1.与对照组比较，后交通动脉瘤组异常后交通动脉（PI型及PII型）发生率高，差异有统计学意义（P0.05）。 2.在动脉瘤组中，P0型、PI型及PII型三种后交通动脉类型的动脉瘤发生率进行两两之间对比，PII型PI型PO型，P值均小于0.05，差别具有统计意义。 3.颈内动脉C1、C2段平均夹角：后交通动脉瘤患侧后交通动脉瘤对侧对照组，差异有统计学意义（P0.05),但是动脉瘤患侧中左、右侧之间角度无差别（P0.05)。结论： 1.异常后交通动脉（PI型及PII型）更易发生后交通动脉瘤，其中PII型后交通动脉最易发生动脉瘤，PI次之，发育正常的PO型后交通动脉最不易发生动脉瘤。 2.颈内动脉C1段、C2段夹角大小与后交通动脉瘤的形成有相关性,该转弯处的夹角较小一侧形成后交通动脉瘤的可能性较大，但左、右侧无明显差别。
[Abstract]:Objective: to investigate the relationship between posterior communicating artery variation and the change of hemodynamics caused by the angle of C _ 1 C _ 2 segment of internal carotid artery and the formation of posterior communicating artery aneurysm. Methods: from January 2008 to December 2013, 76 patients with posterior communicating aneurysm were selected from Department of Neurology, second affiliated Hospital of Dalian Medical University. Seventy-eight patients with non-intracranial aneurysms in the same period were randomly selected and all of them were examined by cerebrovascular angiography. According to the blood supply type of posterior cerebral artery, the posterior communicating artery was divided into three types: type: PO. Pi type and PII type. The number of posterior communicating artery was counted in aneurysm group and control group. Compared with the control group (non-aneurysm group). At the same time statistics of the three types of posterior communicating artery aneurysm in the aneurysm group, the three groups were compared. According to the cerebral angiography film. The angle between C1 segment and C2 segment of the internal carotid artery (i.e. near the multiple sites of the posterior communicating artery) of the posterior communicating artery aneurysm was measured. And compared with the control group (non-aneurysm group), the statistical software SPSS17.0 was used to analyze the data, the counting data was chi-square test, and the measurement data was t-test. P0.05 indicated that the difference was statistically significant (P0.01). Results: 1.Compared with the control group, the incidence of Pi type and PII type of posterior communicating artery aneurysm in the patients with abnormal posterior communicating artery aneurysm was higher than that in the control group, and the difference was statistically significant (P 0.05). 2. The incidence of aneurysms of three types of posterior communicating artery (P0 and PII) in aneurysm group was compared with that in PII type Pi type PO group (P < 0 05). The difference has statistical significance. 3. The mean angle of C _ 1 C _ 2 segment of internal carotid artery: the contralateral control group of posterior communicating artery aneurysm, the difference was statistically significant (P 0.05), but the middle left side of the aneurysm. There was no difference in the angle between the right side (P 0.05). Conclusion: 1. Pi type and PII type of abnormal posterior communicating artery are more likely to occur posterior communicating artery aneurysm, among which PII type posterior communicating artery is the most likely to develop Pi aneurysm. The aneurysms of the posterior communicating artery are most difficult to occur in the normal development of PO type. 2. The angle between C1 segment and C2 segment of internal carotid artery was correlated with the formation of posterior communicating artery aneurysm. The angle at the corner was more likely to form the posterior communicating artery aneurysm, but there was no significant difference between the left and the right side.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R743.3

【参考文献】