脑微出血与椎-基底动脉形态在脑干梗死中的相关性研究

发布时间：2018-02-03 19:46

本文关键词： 脑微出血磁敏感加权成像脑干梗死椎-基底动脉血管形态　出处：《临床神经病学杂志》2017年04期 　论文类型：期刊论文

【摘要】：目的研究脑干梗死患者脑微出血(CMBs)与椎-基底动脉形态的关系。方法对204例脑干梗死患者行头颅MRI+磁敏感加权成像(SWI)及头颈MRA检查,根据CMBs情况将患者分为脑干CMBs阳性组与阴性组。比较两组椎-基底动脉形态特点,分析脑干梗死患者CMBs与椎-基底动脉形态独立相关因素。结果头颅SWI检查结果显示,112例患者有脑干CMBs(阳性组),92例脑干无CMBs(阴性组)。阳性组椎-基底动脉异常发生率(78.6%)显著高于阴性组(58.7%)(χ~2=9.432,P=0.002)。与阴性组比较,阳性组椎动脉狭窄、椎动脉发育不良及基底动脉迂曲、延长的比率显著增高(均P0.05)。Logistic回归分析显示,椎动脉发育不良、基底动脉迂曲延长是脑干脑CMBs的独立危险因素(OR=1.859,95CI%:1.056~3.270,P=0.032;OR=1.745,95CI%:1.010~3.018,P=0.046)。结论伴有椎-基底动脉形态异常脑干梗死患者脑干CMBs发生率高。脑干CMBs与椎动脉发育不良、基底动脉迂曲延长独立相关。
[Abstract]:Objective to study the relationship between cerebral microhemorrhage and the morphology of vertebrobasilar artery in patients with brainstem infarction. Methods the cranial MRI magnetic sensitivity weighted imaging (MRI) was performed in 204 patients with brainstem infarction. And head and neck MRA. According to the CMBs, the patients were divided into two groups: brainstem CMBs positive group and negative group. The morphological characteristics of vertebrobasilar artery were compared between the two groups. Objective: to analyze the independent correlation factors between CMBs and the morphology of vertebrobasilar artery in patients with brainstem infarction. Results the results of cranial SWI showed that there were 112 patients with brainstem CMBspositive group. The abnormal rate of vertebrobasilar artery in the positive group was significantly higher than that in the negative group (蠂 2 = 9.432). Compared with the negative group, the positive group had vertebral artery stenosis, vertebral artery dysplasia and basilar artery twisting. The rate of prolongation was significantly higher (all P0.05. logistic regression analysis showed that vertebral artery dysplasia. The extension of basilar artery was an independent risk factor of CMBs in brainstem brain. Orl 1.745 95 CI: 1.010 / 3.018. Conclusion there is a high incidence of CMBs in patients with brainstem infarction with vertebrobasilar artery malformation. There is an independent correlation between brain-stem CMBs and vertebral artery dysplasia and basilar artery detour lengthening.
【作者单位】：河北北方学院;邯郸市中心医院神经内二科;
【分类号】：R743.33
【正文快照】： 作者单位:075000张家口,河北北方学院(刘超);邯郸市中心医院神经内二科(李军涛,霍会永,曹凌)脑干梗死具有病情凶险、演变快、并发症多、病死率高的特点,是缺血性脑血管病中较为严重临床类型[1]。椎-基底动脉为脑干的主要供血血管,其形态变化多样,多伴有血流动力学、解剖位置改

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