老年脑卒中患者癫痫发作的临床特点、脑电图表现及其危险因素分析

发布时间：2018-02-13 20:56

  本文关键词： 脑卒中后癫痫 老年人 临床特点 脑电图 危险因素　出处：《国际神经病学神经外科学杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨老年人群脑卒中后癫痫(PSE)发作的临床特点、脑电图表现及其危险因素,为癫痫的早期预防提供依据。方法选取儋州市人民医院收治的脑卒中患者1485例,最终纳入患者992例,分析患者的临床特点及脑电图表现。根据脑卒中后癫痫发作情况,将其分为癫痫发作组87例和无癫痫发作组905例。应用单因素及多因素Logistic回归分析PSE的危险因素。结果 PSE的发生率为8.77%,其中早发型癫痫占55.17%,迟发型癫痫占44.83%。PSE发作的脑电图呈弥散性异常占26.44%,局限性异常占48.28%。单因素及多因素Logistic回归分析显示,高同型半胱氨酸血症、病灶部位、病灶范围、电解质紊乱、日常生活能力及NIHSS评分≥25分是PSE发作的独立危险因素,其OR(95%CI)值分别为2.063(1.146~3.125)、6.285(5.168~9.047)、4.725(3.684~6.835)、3.029(2.016~4.532)、2.538(1.568~3.562)和3.163(2.085~4.726)。结论老年人群脑卒中后癫痫发作的发生率较高,影响癫痫发作的危险因素较多,对存在危险因素的患者应高度警惕其癫痫的发生。
[Abstract]:Objective to investigate the clinical features, electroencephalogram (EEG) manifestations and risk factors of PSEs after stroke in elderly people, and to provide evidence for early prevention of epilepsy. Methods 1485 stroke patients treated in Danzhou people's Hospital were selected. Finally, 992 patients were included. The clinical characteristics and EEG manifestations of the patients were analyzed. The risk factors of PSE were analyzed by univariate and multivariate Logistic regression analysis. Results the incidence of PSE was 8.770.The incidence of early epilepsy was 55.17, and the rate of delayed epilepsy was 44.833.PSEs were used to analyze the risk factors of Epilepsy group (n = 87) and non-epileptic seizure group (n = 905). The risk factors of PSE were analyzed by univariate and multivariate Logistic regression analysis. The electroencephalogram was diffusely abnormal in 26.44% and localized in 48.28%. Univariate and multivariate Logistic regression analysis showed that, Hyperhomocysteinemia, lesion location, focal area, electrolyte disturbance, ADL and NIHSS score 鈮，

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