首次卒中患者卒中部位与卒中后抑郁相关性的Meta分析

发布时间：2018-02-21 21:03

本文关键词： 卒中抑郁卒中部位相关性 Meta分析　出处：《重庆医学》2017年19期 　论文类型：期刊论文

【摘要】：目的系统评价首次卒中患者卒中部位与卒中后抑郁(PSD)的关系。方法检索中文科技期刊数据库(VIP)、相关期刊论文(CNKI)、万方数据库、PubMed、ISI Web of Science、Ovid全文数据库、Elsevier Science Direct等国内外数据库1980年1月至2016年3月发表的卒中部位与PSD相关性的研究。采用RevMan5.3软件进行数据合并分析。结果共纳入14项研究,1 952例患者。Meta分析显示:首次卒中患者卒中部位与PSD的发生无直接相关性[随机效应模型,95%CI(0.89,1.43),P0.01];亚组分析结果显示,使用汉密尔顿抑郁量表(HAMD)进行评估时右侧卒中部位与PSD的发生相关[固定效应模型,95%CI(1.21,1.76),P0.01],而在卒中后的病程、卒中后患者有无失语上PSD的发生与卒中部位无明显相关性。结论首次卒中患者卒中部位与PSD不具有直接相关性,未来研究需作进一步的探讨。
[Abstract]:Objective to systematically evaluate the relationship between stroke site and post stroke depression (PSD) in patients with first stroke. Methods to search the database of Chinese sci-tech periodicals (VIPP), CNKI (full text Database of Chinese Journals), PubMedi Web of Ovid (Wanfang Database) and Elsevier Science Direct, etc. A study on the correlation between stroke site and PSD was published in internal and external databases from January 1980 to March 2016. The data were combined with RevMan5.3 software. The results included 14 studies, including 1,952 patients. Meta-analysis showed that: first stroke patients. There was no direct correlation between the location of stroke and the occurrence of PSD. The right stroke site was associated with the occurrence of PSD when evaluated with Hamilton Depression scale (Hamd) [Fixed-effect model: 95CI1.21 1.76 P0.01], and the course of stroke after stroke, There is no significant correlation between the occurrence of PSD and the location of stroke after stroke. Conclusion there is no direct correlation between the location of stroke and PSD in the first stroke patients, and further study is needed in the future.
【作者单位】：苏州大学第一附属医院神经外科;苏州大学护理学院;
【基金】：2016年度重庆市出版专项资金资助项目
【分类号】：R743.3

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