大脑中动脉狭窄和微栓子关系的临床研究

发布时间：2018-02-24 03:20

本文关键词： 大脑中动脉狭窄病理性脑梗塞经颅多普勒微栓子信号　出处：《现代实用医学》2015年04期 　论文类型：期刊论文

【摘要】：目的探讨微栓子信号(MES)与大脑中动脉狭窄(MCAS)的相关性。方法选取症状性MCAS患者70例,无症状性MCAS患者20例;症状性MCAS组又分为短暂性脑缺血发作(TIA)组14例和脑梗死组56例。所有患者均行头颅MRI证实有无梗死灶,并记录梗死部位;行CT血管成像(CTA)或数字减影血管造影(DSA)对大脑中动脉有无狭窄以及狭窄程度进行分级;行MES监测,记录栓子数量、部位。结果症状性MCAS组MES阳性率高于无症状组(0.05);症状性MCAS组,轻、中、重度狭窄3组的MES阳性率差异有统计学意义(0.05);症状性MCAS组MES阳性的患者美国国立卫生院神经功能缺损评分(NIHSS)低于阴性患者(0.05);症状性MCAS组交界区梗死和散发皮质小梗死MES阳性率明显高于其他梗死类型(0.05)。结论充分评估脑血管影像学检查,结合MES监测,对于不同类型的脑梗死采用个体化治疗。
[Abstract]:Objective to investigate the relationship between microembolus signal and middle cerebral artery stenosis (MCAS). Methods 70 patients with symptomatic MCAS and 20 patients with asymptomatic MCAS were selected. The symptomatic MCAS group was divided into two groups: TIA group (n = 14) and cerebral infarction group (n = 56). All the patients were confirmed by cranial MRI and the location of infarction was recorded. Ct angiography and digital subtraction angiography were used to grade middle cerebral artery stenosis and degree of stenosis. MES monitoring was performed to record the number and location of emboli. Results the positive rate of MES in symptomatic MCAS group was higher than that in asymptomatic MCAS group, the positive rate of MES in symptomatic MCAS group was higher than that in asymptomatic MCAS group, and in symptomatic MCAS group, the positive rate of MES in symptomatic MCAS group was higher than that in asymptomatic MCAS group. Light, medium, There were significant differences in MES positive rate among the three groups with severe stenosis, the MES positive MES score in the symptomatic MCAS group was lower than that in the negative MCAS group, and the infarct and sporadic cortex in the symptomatic MCAS group were smaller than those in the symptomatic MCAS group. The positive rate of MES in infarction was significantly higher than that in other types of infarction. Combined with MES monitoring, individual treatment was used for different types of cerebral infarction.
【作者单位】：宁波大学医学院附属医院;浙江大学医学院附属第二医院;
【基金】：浙江省科技厅项目(2012C33117)
【分类号】：R743.3

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