高血压患者脑卒中发病影响因素Cox回归分析

发布时间：2018-02-25 02:29

  本文关键词： 脑卒中 发病 影响因素 高血压患者 队列研究 Cox回归分析　出处：《中国公共卫生》2016年06期 　论文类型：期刊论文

【摘要】：目的了解高血压患者脑卒中发病影响因素,为脑卒中的预防控制提供参考依据。方法采用前瞻性队列研究方法于2010年1月,在江苏省5个高血压社区规范化管理基地随机抽取12 893例高血压患者进行问卷调查、体格检查和实验室检测,并就高血压患者的血压控制情况、脑卒中发生情况和死亡情况于2011—2014年每年进行1次随访,采用单因素和多因素Cox回归分析方法分析高血压患者脑卒中发病的影响因素。结果江苏省随访的12 893例高血压患者随访时间为0.7~58.1个月,平均随访时间为(43.4±10.2)个月,共失访554例,失访率为4.30%;随访结束时高血压患者脑卒中发病331例,脑卒中发病率为2.68%;多因素Cox回归分析结果显示,年龄≥45岁、高血压病程5年、有脑卒中家族史、收缩压≥180 mm Hg和左心室肥厚为高血压患者脑卒中发病的危险因素,女性和文化程度初中及以上为高血压患者脑卒中发病的保护因素。结论性别、年龄、文化程度、高血压病程、脑卒中家族史、收缩压和左心室肥厚是高血压患者发生脑卒中的主要影响因素。
[Abstract]:Objective to investigate the influencing factors of stroke in patients with hypertension and to provide reference for the prevention and control of stroke. Methods A prospective cohort study was conducted on January 2010. A total of 12 893 hypertension patients were randomly selected from 5 hypertension community standardized management bases in Jiangsu Province for questionnaire investigation, physical examination and laboratory examination. The incidence and death of stroke were followed up once a year in 2011-2014, Univariate and multivariate Cox regression analysis was used to analyze the influencing factors of stroke in patients with hypertension. Results 12 893 patients with hypertension were followed up in Jiangsu Province for 0.7 ~ 58.1 months, with an average follow-up time of 43.4 卤10.2 months. At the end of follow-up, 331 cases of hypertensive stroke and 2.68% of stroke incidence were found. The results of multivariate Cox regression analysis showed that age 鈮，

本文编号：1532699