动脉瘤性蛛网膜下腔出血致迟发性脑血管痉挛危险因素的Meta分析

发布时间：2018-02-26 00:07

本文关键词： 蛛网膜下腔出血迟发性脑血管痉挛危险因素 Meta分析　出处：《重庆医学》2014年14期 　论文类型：期刊论文

【摘要】：目的运用Meta分析方法综合分析动脉瘤性蛛网膜下腔出血致迟发性脑血管痉挛(DCVS)的相关危险因素,为疾病的预防、治疗决策提供依据。方法用关键词途径从维普中文科技期刊、中国知网和万方以及Pubmed、Springlink和Highwire等外文数据库收录有关动脉瘤性蛛网膜下腔出血致DCVS相关危险因素的文献进行检索,经严格筛选后对最后纳入的文献用RevMan5.1软件进行Meta分析。结果共纳入13篇文献,经检验所有数据均均衡,采用固定效应模式进行Meta分析。高血压病史、Fisher分级(2级)、年龄(50岁)、动脉瘤位置(后循环)差异有统计学意义(P0.05),性别(男性)、吸烟史、手术方式(夹闭)差异无统计学意义(P0.05)。数据漏斗图分析对称,提示文献无发表偏倚。结论有高血压病史、Fisher分级(2级)、年龄(50岁)、动脉瘤位置(后循环)的患者更易发生DCVS,临床上应对此类患者加强监测与管理。
[Abstract]:Objective to analyze the risk factors of delayed cerebral vasospasm caused by aneurysm subarachnoid hemorrhage (SAH) by means of Meta analysis, so as to provide the basis for disease prevention and treatment decision. The literature on the risk factors related to DCVS caused by aneurysm subarachnoid hemorrhage (SAH) was retrieved in the database of China Zhiwang and Wanfang, as well as Pubmedan Spring link and Highwire. The final literature was analyzed by Meta with RevMan5.1 software after strict screening. The results showed that 13 articles were included, and all the data were balanced. Fixed-effect model was used to analyze Meta. There were significant differences in aneurysm location (posterior circulation) between male and female (male, smoking history). There was no significant difference in operation (clamping). The data funnel graph was symmetrical. Conclusion DCVSs are more likely to occur in patients with history of hypertension and Fisher grade 2, age 50 years old and aneurysm location (posterior circulation). Monitoring and management of DCVSs should be strengthened clinically.
【作者单位】：重庆医科大学附属第二医院神经外科;
【分类号】：R743.3

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