血管迷走性晕厥伴有高血压病患者临床资料分析

发布时间：2018-02-26 08:24

本文关键词： 高血压病血管迷走性晕厥直立倾斜试验　出处：《扬州大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的： (1).观察伴或不伴有高血压病的血管迷走性晕厥患者的临床特点及实验室指标,探索血管迷走性晕厥潜在的病理生理学机制。分析两组患者直立倾斜试验中血压变化、住院期间用药方案及治疗转归,探讨合并高血压病的血管迷走性晕厥患者合理的治疗方案。 (2).比较所有入选血管迷走性晕厥患者服用β受体阻滞剂情况,分析β受体阻滞剂在血管迷走性晕厥中的作用。方法：统计分析出院诊断为血管迷走性晕厥合并高血压病的30例住院患者与单纯诊断血管迷走性晕厥30例住院患者的临床特点,与纳入的30例健康体检者比较三组间的一般情况及实验室指标,并通过记录比较伴或不伴高血压病的血管迷走性晕厥患者两组间直立倾斜试验中的血压变化及治疗特点,评价合并高血压病的血管迷走性晕厥患者的临床特点及合适的治疗方案。结果： (1).伴或不伴高血压病的血管迷走性晕厥患者与健康对照组间一般资料、实验室指标差异无统计学意义(P0.05)。 (2).伴高血压病的血管迷走性晕厥患者平卧位血压显著高于不伴高血压的血管迷走性晕厥患者(P0.05),倾斜后两组之间血压变化无统计学意义(P0.05)。 (3).在降压药物应用方面,合并高血压病的血管迷走性晕厥患者有80%坚持服用降压药物控制血压。 (4).合并高血压病的VVS患者中共有11例(36.7%)服用β受体阻滞剂药物进行治疗,非高血压病的VVS患者中有4例(13%)服用p受体阻滞剂药物进行治疗,两组间指标差异有统计学意义(P0.05)。服或不服用p受体阻滞剂药物的血管迷走性晕厥患者在年龄、性别、入院时心率、病程、晕厥发作诱因及晕厥先兆、发作次数、持续时间等方面差异性均无统计学意义(P0.05)。结论： (1).合并高血压病的血管迷走性晕厥患者平卧位血压明显高于不伴高血压的血管迷走性晕厥患者,倾斜后血压两组间变化无显著性差异。对合并高血压病的血管迷走性晕厥患者应选择合理的降压和综合治疗方案。 (2).β受体阻滞剂是目前治疗血管迷走性晕厥的基本药物,有关β受体阻滞剂在血管迷走性晕厥治疗中的价值和特异性尚需扩大样本进一步研究。
[Abstract]:Objective:. To observe the clinical characteristics and laboratory indexes of vasovagal syncope with or without hypertension, and to explore the underlying pathophysiological mechanism of vasovagal syncope. To explore the rational treatment of vasovagal syncope complicated with hypertension. To compare the effects of 尾 receptor blockers on vasovagal syncope in all patients with vasovagal syncope. Methods:. The clinical features of 30 patients with vasovagal syncope complicated with hypertension and 30 patients with vasovagal syncope diagnosed by simple diagnosis of vasovagal syncope were analyzed statistically. The general situation and laboratory indexes of the three groups were compared with 30 healthy persons, and the changes of blood pressure and the characteristics of treatment in the vertical tilt test between the two groups were recorded and compared with or without hypertension. To evaluate the clinical features and appropriate treatment of vasovagal syncope complicated with hypertension. Results:. There was no significant difference in laboratory indexes between patients with vasovagal syncope with or without hypertension and healthy control group (P 0.05). The blood pressure in supine position in patients with vasovagal syncope with hypertension was significantly higher than that in patients with vasovagal syncope without hypertension (P 0.05). 80% patients with vasovagal syncope with hypertension take antihypertensive drugs to control blood pressure. A total of 11 VVS patients with hypertension were treated with beta-receptor blockers, and four patients with non-hypertensive VVS were treated with p-receptor blockers. The difference between the two groups was statistically significant (P 0.05). Patients with vasovagal syncope who took or did not take p receptor blockers were treated with age, sex, heart rate at admission, course of illness, onset of syncope, symptoms of syncope, frequency of attack. The difference of duration was not statistically significant (P 0.05). Conclusion:. In patients with vasovagal syncope complicated with hypertension, the blood pressure in supine position was significantly higher than that in patients with vasovagal syncope without hypertension. There was no significant difference in blood pressure between the two groups after tilt. The patients with vasovagal syncope complicated with hypertension should choose reasonable hypotension and comprehensive treatment. 尾 -blocker is a basic drug for the treatment of vasovagal syncope. The value and specificity of 尾 -blocker in the treatment of vasovagal syncope need to be further studied.
【学位授予单位】：扬州大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R741

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