电刺激犬肝脏对心电活动及肝组织的影响

发布时间：2018-03-01 17:19

本文关键词： 起搏器电极心电变化局部肝组织肝功能肝组织学　出处：《重庆医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的:探讨长期脉冲电刺激肝脏局部对心电活动的影响；长期脉冲电刺激肝脏对肝功能及肝组织学的影响。方法:重庆黄犬1条，人工永久起搏器电极连接于肝脏右叶表面，关闭起搏器感知功能，，起搏频率100次/分，起搏电压5伏，作为长期脉冲电刺激器用。观察心电图3月。结果: 1）脉冲电刺激肝脏心电图(ECG)未见明显改变。 2）脉冲电刺激肝脏未导致犬生活行为改变，肝功能正常。 3）电极连接处肝脏组织结缔组织轻度增生。结论: 1）电压5伏、频率100次/分、持续3月的脉冲电刺激犬肝脏对心电活动基本无影响。 2）电压5伏、频率100次/分、持续3月的脉冲电刺激犬肝脏，电极连接处肝组织轻度结缔组织增生，其余肝组织无改变，肝功能检测正常。
[Abstract]:Objective: To investigate the effect of long-term pulse electric stimulation on the liver function and the effect of long-term pulse electric stimulation on liver function and liver histology.
Methods: Chongqing yellow dog 1, artificial pacemaker electrode is connected to the right lobe of the liver surface, close the pacemaker sensing function, pacing pacing frequency 100 / min, 5 volts, as long as the electrical stimulator. The electrocardiogram was March.
Result:
1) there was no significant change in the electrocardiogram (ECG) of the liver with pulse electric stimulation.
2) pulse electric stimulation of the liver did not cause changes in the living and behavior of the dog, and the liver function was normal.
3) mild hyperplasia of connective tissue in the liver tissue at the electrode junction.
Conclusion:
1) 5 volts, frequency of 100 beats per minute, basically last March pulsed electrical stimulation of canine liver had no effect on the electrical activity of the heart.
2) 5 volts, frequency 100 times / min, pulsed electrical stimulation of canine liver last March, slight proliferation of connective tissue at the electrode is connected with the rest of liver tissue, liver tissue changes, liver function was normal.

【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R745

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