降压药降低中风风险的效果评价

发布时间：2018-03-02 04:18

本文关键词： 中风高血压降压药荟萃分析随机对照试验　出处：《重庆医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：中风（Stroke）也叫脑卒中，可分为两种类型：缺血性脑卒中和出血性脑卒中。中风是中医学对急性脑血管疾病的统称。它是以猝然昏倒、不省人事、伴发口角歪斜、语言障碍，同时伴有半身不遂为主要症状和体征的一种疾病。由于本病发病率高、死亡率高、致残率高、复发率高以及并发症多的特点，所以医学界把它同冠心病、癌症并列为威胁人类健康的三大疾病之一。预防和治疗中风的重要性已经在国内外医学界达成共识，医学家们正从各方面探索中风的预防和治疗措施。中风不可纠正的危险因素包括年龄、性别、种族、遗传。可纠正的危险因素包括高血压、心脏病（特别是心房纤颤）、糖尿病、异常脂蛋白血症、吸烟、酗酒、缺乏运动、肥胖及无症状的劲动脉狭窄和短暂性脑缺血发作。高血压是重要的卒中危险因素之一，随着血压的升高，脑卒中的危险性增加，二者呈正相关。控制收缩压和舒张压，有利于降低高血压患者的脑卒中发生率。本研究旨在收集国内、外大型随机对照试验，提取原发性高血压患者在服用各类一线降压药之后，卒中的发病率数据，进行荟萃分析。从而为临床科学防治卒中提供有力的证据，，有效地降低高血压患者脑卒中的发生率。
[Abstract]:Stroke Stroke, also known as stroke, can be divided into two types: ischemic stroke and hemorrhagic stroke. Stroke is a generic term for acute cerebrovascular diseases in traditional Chinese medicine. At the same time, hemiplegia is a disease with major symptoms and signs. Because of its high incidence, high mortality, high disability rate, high recurrence rate and many complications, the medical profession has associated it with coronary heart disease. Cancer is one of the three major diseases threatening human health. The importance of preventing and treating stroke has been agreed in the medical field at home and abroad, and medical scientists are exploring the prevention and treatment of stroke from all aspects. Uncorrectable risk factors for stroke include age, sex, race, heredity. Correctable risk factors include high blood pressure, heart disease (especially atrial fibrillation, diabetes, abnormal lipoproteinemia, smoking, alcoholism, lack of exercise, etc.). Obesity and asymptomatic stenosis of the arteries and transient ischemic attacks. Hypertension is one of the most important risk factors for stroke. With the increase of blood pressure, the risk of stroke increases. The aim of this study was to collect data on the incidence of stroke in patients with essential hypertension after taking various first-line antihypertensive drugs. A meta-analysis was carried out to provide strong evidence for clinical science in the prevention and treatment of stroke and to effectively reduce the incidence of stroke in hypertensive patients.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R544.1;R743.3

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