住院帕金森病患者肢体感觉障碍相关因素分析

发布时间：2018-03-19 03:18

本文选题：帕金森病　切入点：肢体感觉障碍　出处：《昆明医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：[目的]尝试寻找帕金森病非运动症状中肢体感觉障碍的发生的相关因素,初步讨论各因素之间的联系。[方法]查阅昆明医科大学第一附属医院神经内科2014年1月1日至2016年12月31日三年内全部收治的主要诊断为帕金森病的共190名患者病案资料。将其按是否伴发肢体疼痛、是否伴发肢体麻木和是否伴发肢体无力进行分组。记录其性别、年龄、发病年龄、住院时间、病程、首发症状、吸烟饮酒史以及合并疾病,利用SPSS软件对各组因素之间进行两样本t检验、中位数检验、Mann-Whitney U检验、四格表卡方检验、Logistic回归分析,P0.05表示差异有统计学意义。相关结果列表或作图显示。[结果]吸烟史与帕金森病患者发生肢体疼痛呈正相关[P=0.003 OR=3.079(1.417-6.690)];合并高血压和帕金森病患者发生肢体麻木呈负相关[P=0.027 OR=0.333(0.121-0.917)];合并低钾血症与帕金森病患者发生肢体麻木呈正相关相关[P=0.037 OR=2.463(1.038-5.847)];首发症状与帕金森患者发生肢体无力有相关性[P=0.000]。帕金森病患者发生肢体疼痛的独立因素是吸烟史[P=0.005,OR=3.054(1.405-6.637)];帕金森病患者发生肢体麻木的独立因素是高血压[P=0.026,OR=0.311(0.111-0.873)]、低钾血症[P=0.023,OR=2.826(1.157-6.903)];帕金森患者发生肢体无力的独立影响因素为首发症状和住院时间[P=0.042,OR=1.129(1.005-1.269)]。[结论]有吸烟史的帕金森病患者更易发生肢体疼痛;低钾血症是帕金森病患者发生肢体麻木症状的危险性因素;合并高血压的帕金森病患者更不易出现肢体麻木症状;首发症状、住院时间与肢体无力症状之间有相关性。
[Abstract]:[Objective] to try to find Parkinson's disease symptoms in non limb sensory disturbance occurred related factors, preliminary discuss the diagnosis method. Relationship between various factors] refer to the First Affiliated Hospital of Kunming Medical University Department of Neurology from January 1, 2014 to December 31, 2016 three years all were the main medical records for a total of 190 patients with Parkinson's disease. According to whether with hair limb pain, numbness and concomitant concomitant limb weakness group. Record the gender, age, age of onset, duration of hospitalization, course of disease, symptoms, smoking and drinking history and comorbidities, two sample t test between groups using SPSS software on the Mann-Whitney factor median test, U test, four table chi square test, Logistic regression analysis, P0.05 said the difference was statistically significant. The mapping list or history of smoking and Parkinson. Result] In patients with limb pain was positively related to [P=0.003 OR=3.079 (1.417-6.690)]; occurrence of numbness is negatively related to [P=0.027 and OR=0.333 with hypertension in patients with Parkinson disease (0.121-0.917)]; with hypokalemia and Parkinson's disease patients with limb numbness was positively related to the relevant [P=0.037 OR=2.463 (1.038-5.847)]; the first symptom in patients with limb weakness and Parkinson independent factors related to Parkinson's disease [P=0.000]. patients with limb pain is the smoking history of [P=0.005, OR=3.054 (1.405-6.637)]; independent factors in patients with Parkinson's disease occurred numbness is hypertension [P=0.026, OR=0.311 (0.111-0.873)], hypopotassaemia [P=0.023, OR=2.826 (1.157-6.903)]; Parkinson were independent factors affecting limb weakness as the first symptom and the hospitalization time [P=0.042, OR=1.129 (1.005-1.269)].[Conclusion] smoking is more likely to occur in patients with Parkinson disease Limb pain; hypokalemia is a risk factor for limb numbness in patients with Parkinson's disease. Patients with Parkinson's disease with hypertension are more likely to have limb numbness symptoms. There is a correlation between first symptom, hospitalization time and limb weakness symptoms.

【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R742.5

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