中西医结合治疗对脑梗死病人血液流变学、超氧化物歧化酶活性和神经功能的影响

发布时间：2018-03-19 18:49

本文选题：中西医　切入点：急性脑梗死　出处：《中华中医药学刊》2017年02期 　论文类型：期刊论文

【摘要】：目的:探索中西医结合治疗对急性脑梗死(ACI)病人血液流变学、超氧化物歧化酶(SOD)及神经功能的影响。方法:将2015年1月—2016年6月期间医院神经内科接诊的116例ACI患者选为临床研究病例,经临床检查确诊后进行编号,并将单双号分成两组,均接受常规内科综合治疗,而对照组58例(单号)应用神经节苷脂钠注射液,观察组58例(双号)在对照组基础上加用丹参川芎嗪注射液治疗,分析临床治疗效果。结果:观察组治疗有效率89.66%与对照组68.97%相比较明显提高(P0.05)。观察组患者治疗后全血高切黏度(5.80±0.36)m Pa·s、全血低切黏度(7.83±0.99)m Pa·s、血浆黏度(1.79±0.34)m Pa·s、红细胞压积(43.56±3.06)%及纤维蛋白原(3.76±0.35)g/L,与治疗前和对照组相比较均明显降低,上述差异均有统计学意义(P0.05)。对照组与观察组治疗后NIHSS评分分别为(19.44±2.03)和(10.41±1.76),与治疗前相比较均明显减少(P0.05);而Barthel指数分别为(54.23±4.93)和(65.83±5.76),与治疗前相比较均明显增加(P0.05);且上述指标两组间比较差异有统计学意义(P0.05)。对照组与观察组治疗后SOD分别为(154.34±9.21)U/m L和(188.30±10.62)U/m L,与治疗前相比较均明显增加(P0.05);且两组间比较差异有统计学意义(P0.05)。结论:中西医结合治疗ACI疗效显著,可改善患者血液流变学指标,升高SOD活性,促进神经功能恢复,提高日常生活能力,值得临床借鉴和推广应用。
[Abstract]:Objective: To explore the combination of traditional Chinese and Western Medicine on the treatment of acute cerebral infarction (ACI) blood rheology, superoxide dismutase (SOD) and the influence of nerve function. Methods: from January 2015 to June 2016 during the 116 cases of ACI patients with hospital admissions for clinical study of the patients, clinically diagnosed after the number, and will single, divided into two groups, were treated with routine medical therapy, and 58 cases in the control group (odd numbers) application of ganglioside sodium injection, 58 cases in observation group (Shuang Hao) in the control group based on the use of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection treatment, analysis of clinical treatment. Results: the effective rate of the treatment group and the control group 68.97% compared to 89.66% increased (P0.05). Observation group after treatment in patients with high blood viscosity (5.80 + 0.36) m Pa - s, low blood viscosity (7.83 + 0.99) m, Pa, s, plasma viscosity (1.79 + 0.34) m Pa - s, hematocrit (43.56 + 3.06)% and Fibrinogen (3.76 + 0.35) g/L, compared with before treatment and the control group were significantly lower, the differences were statistically significant (P0.05). The control group and the observation group after treatment, NIHSS scores were (19.44 + 2.03) and (10.41 + 1.76), compared with before treatment were significantly reduced (P0.05); while the Barthel index respectively (54.23 + 4.93) and (65.83 + 5.76), compared with before treatment were significantly increased (P0.05); and the index difference between the two groups was statistically significant (P0.05). The control group and the observation group after treatment SOD were (154.34 + 9.21) U/m and L (188.30 + 10.62) U/m L, compared with before treatment were significantly increased (P0.05); and there was significant difference between two groups (P0.05). Conclusion: the combination of traditional Chinese and Western medicine treatment of ACI has obvious curative effect, can improve the hemorheology, increase the activity of SOD, promote the recovery of neural function and improve daily life the ability to borrow, it is worthy of clinical Identification and application.

【作者单位】：湖州市第一人民医院;
【分类号】：R743.33

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