单侧大脑中动脉狭窄的容积CT灌注研究

发布时间：2018-03-25 10:34

本文选题：大脑中动脉　切入点：动脉闭塞性疾病　出处：《中国医学影像学杂志》2017年02期

【摘要】：目的探讨128层容积CT脑灌注评价大脑中动脉(MCA)重度狭窄或闭塞病变的临床价值。资料与方法收集2013年7月-2014年12月武汉市第一医院收治的单侧MCA重度狭窄或闭塞患者35例,行容积CT脑灌注扫描并获得CTP容积灌注参数,包括脑血流量(CBF)、脑血容量(CBV)、达峰时间(TTP)、平均通过时间(MTT),同时获得动态CT血管成像(4D-CTA)图像。结果 3例患者表现为TTP延迟,CBF、CBV、MTT未见明显差异。32例病变区CBF较对侧降低,但差异无统计学意义(P0.05);CBV增加、TTP和MTT延长,差异有统计学意义(P0.05)。Mc Nemar检验显示4D-CTA与DSA诊断MCA闭塞差异无统计学意义(P0.05),且两者一致性较好(Kappa=0.861,P0.05)。结论 128层容积CT脑灌注能同时明确MCA重度狭窄或闭塞患者的脑灌注异常和血管狭窄,具有重要的临床价值。
[Abstract]:Objective to evaluate the clinical value of cerebral perfusion with 128-slice volume CT in the evaluation of severe stenosis or occlusion of middle cerebral artery (MCA). Data and methods 35 patients with unilateral severe stenosis or occlusion of MCA were collected from July 2013 to December 2014 in Wuhan first Hospital. The volume perfusion parameters of CTP were obtained by cerebral perfusion scanning with volume CT. Among them, CBFV, CBV, TTP, mean transit time (MTT) and dynamic CT angiography (4D-CTA) images were obtained. Results there was no significant difference in the CBF of 32 patients with TTP delayed CBFV. However, there was no significant difference in the increase of TTP and MTT. The difference was statistically significant (P 0.05). Mc Nemar test showed that there was no significant difference between 4D-CTA and DSA in the diagnosis of MCA obliteration, and there was good consistency between them. Conclusion 128-slice CT perfusion can identify cerebral perfusion in patients with severe MCA stenosis or occlusion at the same time. Abnormalities and stenosis of blood vessels, It has important clinical value.
【作者单位】：武汉市第一医院放射科;
【基金】：武汉市卫计委临床医学科研项目(WX12C42)
【分类号】：R743.3

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