颅内脑膜瘤单中心845例临床病理分析

发布时间：2018-03-26 15:07

  本文选题：脑膜瘤　切入点：生存分析　出处：《广东医学》2017年24期

【摘要】：目的分析15年间单中心颅内脑膜瘤患者临床及病理特征和治疗效果。方法回顾性分析845例手术治疗的脑膜瘤患者的临床病理及预后资料,应用Kaplan-Meier法、log-rank检验和Cox回归模型对性别、年龄、WHO病理级别、术前KPS评分等临床病理特征进行单因素和多因素生存分析。结果 845例脑膜瘤患者中男235例,女610例,年龄(49.96±12.17)岁,总随访时间1~240个月,中位随访时间5.00个月。57例术后复发,其中WHOⅠ级脑膜瘤复发36例(4.9%,36/732),WHOⅡ级脑膜瘤复发14例(17.1%,14/82),WHOⅢ级脑膜瘤复发7例(7/31)。WHO病理分级高和男性是脑膜瘤复发高危因素。结论 WHOⅡ和Ⅲ级脑膜瘤手术后易复发,对于高危患者需要采取积极辅助治疗并严密随访。
[Abstract]:Objective to analyze the clinical and pathological features and therapeutic efficacy of patients with monocentric meningioma during the past 15 years. Methods the clinicopathological and prognostic data of 845 patients with intracranial meningioma treated by surgery were analyzed retrospectively, and the sex was analyzed by Kaplan-Meier 's log-rank test and Cox regression model. Results among 845 patients with meningioma, 235 were male, 610 were female, the age was 49.96 卤12.17 years old, and the total follow-up time was 1 ~ 240 months. The median follow-up time was 5.00 months. Among the 36 cases of WHO 鈪，

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