多导定量分析振幅整合脑电图在脑损伤儿童的临床应用

发布时间：2018-03-28 10:29

本文选题：多导定量分析　切入点：振幅整合脑电图　出处：《中山大学学报(医学科学版)》2017年06期

【摘要】：【目的】探讨脑损伤儿童振幅整合脑电图(a EEG)改变以及与神经系统早期预后的关系。【方法】采用16导联的a EEG监测模式对100例脑损伤患儿(脑损伤组)及100例正常儿童(对照组)进行监测。对两组儿童不同年龄段额、中央、顶、颞区的波谱进行比较,比较脑损伤组儿童急性期及1周后a EEG特点,分析脑损伤儿童的a EEG特点。同时随访记录3个月后脑损伤组儿童脑功能等级评分(PCPC),并评价脑损伤儿童a EEG的变化与PCPC评分的相关性。【结果】2-12月正常婴儿与异常婴儿下边界电压相比额区、颞区明显增高(P0.05);带宽的比较,额区、中央区、颞区脑损伤婴儿较正常婴儿明显降低(P0.05)。13-35月的脑损伤儿童与正常对照组a EEG比较表明:所有导联的上边界及下边界电压均较正常组明显增高(P0.05)。36-71月脑损伤儿童与正常儿童下边界电压相比额区、中央区、顶区、颞区明显增高(P0.05);上边界的比较中仅额区、顶区差异具有统计学意义(P0.05)。72-155月脑损伤儿童与正常儿童下边界电压相比额区、中央区、顶区、颞区明显增高(P0.05);上边界的比较中仅额区、中央区、顶区差异具有统计学意义(P0.05);带宽比较额区、顶区两组间比较差异有统计学意义(P0.05)。156-216月脑损伤儿童与正常儿童下边界电压相比额区、中央区、顶区、颞区明显增高(P0.05);上边界的比较中额区、中央区、顶区、颞区明显增高(P0.05);带宽比较仅额区两组间比较差异有统计学意义(P0.05)。脑损伤患儿3个月后的PCPC评分与患儿a EEG进行相关分析表明顶区上边界、下边界存在相关性,相关系数分别为0.222,0.219。【结论】脑损伤儿童的各导联下边界电压发生改变,脑损伤患儿早期顶区a EEG定量值可用于预测患儿的近期预后。
[Abstract]:[objective] to investigate the changes of amplitude-integrated electroencephalogram (EEG) and its relationship with early prognosis of nervous system in children with brain injury. [methods] A EEG monitoring model with 16 leads was used in 100 children with brain injury (brain injury group) and 100 patients with positive brain injury. Normal children (control group) were monitored. The spectra of central, parietal and temporal regions were compared to compare the characteristics of a EEG in acute stage and 1 week after brain injury group. To analyze the characteristics of a EEG in children with brain injury, and to record the scores of brain function grade in children with brain injury after 3 months of follow-up, and to evaluate the correlation between the changes of a EEG and PCPC score in children with brain injury. [results] the normal infants and abnormal infants in February to December were evaluated. Infantile lower boundary voltage compared to frontal region, The temporal region was significantly increased (P 0.05), the bandwidth was compared, the frontal region, the central region, the central region, the frontal region, the central region, Compared with the normal control group, the EEG of children with brain injury in temporal region was significantly lower than that of normal infants. The results showed that the voltage of upper boundary and lower boundary of all leads were significantly higher than that of normal group. P0.05. 36-71 months of brain injury in children with brain injury and normal were significantly higher than those in normal group. Children's lower boundary voltage compared to the frontal region, The central, parietal and temporal regions were significantly higher than that of normal children, and the frontal, central and parietal areas were significantly higher than those in normal children, while the frontal, central and parietal areas were significantly higher than those in normal children. The difference in parietal area was significant in the frontal area, central region and parietal area in children with brain injury during the period of 72-155 months compared with those in normal children. There were significant differences in the temporal region, the upper border, the frontal region, the central region and the parietal region, and the difference in the bandwidth between the frontal region, the central region and the parietal region, and the comparison of the bandwidth between the frontal region and the parietal region. The difference between the two groups was statistically significant (P 0.05). 156-216 months after brain injury compared with normal children, the lower boundary voltage in frontal, central, parietal and temporal regions were significantly higher than those in normal children, and the middle frontal, central and parietal regions in the comparison of upper border, middle frontal, central and parietal regions. There was significant difference in the bandwidth between the two groups only in the frontal area. The correlation analysis between the PCPC scores of the children with brain injury and the a EEG showed that there was a correlation between the upper and lower boundaries of the parietal region. The correlation coefficients were 0.222n0.219.Conclusion the voltage of the lower lead of children with brain injury changes, and the quantitative value of a EEG in the early parietal region can be used to predict the short-term prognosis of the children with brain injury.
【作者单位】：中山大学附属第一医院妇产科;四川大学华西第二医院儿科;
【分类号】：R726.5;R741.044

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