中国地区短暂性全面性遗忘研究现状及临床特征

发布时间：2018-03-29 00:14

  本文选题：短暂性全面性遗忘　切入点：高血压　出处：《中国老年学杂志》2017年21期

【摘要】：目的探讨中国地区符合Caplan和Hodges诊断标准的短暂性全面性遗忘(TGA)的研究现状及其临床特点。方法检索中国生物医学文献数据库(CBM)、相关期刊论文(CNKI)和维普中文科技期刊数据库(VIP)中文数据库,检索时间均从建库至2015年7月,纳入明确提及TGA且符合纳入标准的研究。结果初检到543篇文献,最终纳入57篇文献,56篇为病例报道,1篇为前瞻性病例对照研究。共纳入339例病例,TGA伴随的基础疾病中前三位是高血压、血脂异常和冠心病;TGA发作时无明显诱因者183例(53.98%),明确提及发作诱因者126例(37.17%),诱因主要包括劳累(57例)、情绪激动(49例)、饮酒(10例)。辅助检查中经颅超声多普勒(TCD)及单光子发射计算机断层扫描(SPECT)对TGA患者的病灶检出率较其他检查方法明显增高(P0.05);而TCD与SPECT相比其检出率无统计学差异(P0.05)。TGA尚无特异性治疗方案,复发率低。结论中国地区有关TGA的研究大多数是病例报道;TGA患者伴随的基础疾病多为心脑血管危险因素,绝大多数TGA患者发作时无诱因,TCD及SPECT检查可能有助于TGA的诊断,该病尚无特异性治疗方案且复发率低。
[Abstract]:Objective to investigate the current status and clinical characteristics of transient comprehensive amnesia (TGA) in China, which meets the diagnostic criteria of Caplan and Hodges. Methods the Chinese biomedical literature database, CNKI (Chinese Journal Full-text Database) and Weipu Chinese were searched. Science and Technology Journals Database (VIP) Chinese Database, The retrieval time was from the construction of the database to July 2015, and included the research that explicitly mentioned TGA and met the inclusion criteria. 56 cases were included as case reports and 1 case control study was carried out. Hypertension was the first three diseases associated with TGA in 339 cases. There were 183 cases of dyslipidemia and coronary heart disease with no obvious inducement during TGA attack, 126 cases (37. 17%) mentioned explicitly as inducement, including 57 cases of tiredness, 49 cases of emotional agitation, 10 cases of alcohol consumption. Single photon emission computed tomography (SPECT) showed that the detection rate of TGA was significantly higher than that of other methods, but there was no significant difference in the detection rate between TCD and SPECT. Conclusion the basic diseases associated with TGA in China are mostly cardiovascular and cerebrovascular risk factors. Most of the patients with TGA may be helpful in the diagnosis of TGA without any inducement. There is no specific treatment and the recurrence rate is low.
【作者单位】： 郑州市第二人民医院;郑州大学第二附属医院;
【分类号】：R741
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本文编号：1678699