脑肿瘤患者术后颅内感染病原学特点及危险因素分析

发布时间：2018-04-02 06:37

  本文选题：脑肿瘤　切入点：颅内感染　出处：《中华医院感染学杂志》2017年21期

【摘要】：目的探讨脑肿瘤患者术后颅内感染病原学特点及危险因素。方法选取医院2013年5月-2016年5月收治的脑肿瘤手术患者920例,统计感染患者病原菌分布,分析颅内感染的危险因素。结果脑肿瘤术后患者颅内感染48例,感染率为5.22%,感染患者共分离出病原菌46株,其中革兰阳性菌14株,占30.44%,革兰阴性菌31株,占67.39%,真菌1株,占2.17%;革兰阴性菌对阿米卡星、庆大霉素、亚胺培南、美罗培南耐药率较高,革兰阳性菌对万古霉素、红霉素、利福平耐药率较高;脑脊液漏、手术持续时间≥3h、后颅窝手术为脑肿瘤术后颅内感染的相关因素;脑脊液漏、手术持续时间≥3h和后颅窝手术为独立危险因素。结论革兰阴性菌为脑肿瘤患者术后颅内感染主要病原菌,颅内感染危险因素较多,应针对病原菌特点及危险因素,采取相应的措施,降低颅内感染。
[Abstract]:Objective to investigate the etiological characteristics and risk factors of intracranial infection in patients with brain tumor after operation.Methods 920 patients with brain tumor were selected from May 2013 to May 2016. The distribution of pathogenic bacteria in infected patients was analyzed and the risk factors of intracranial infection were analyzed.Results there were 48 patients with intracranial infection after operation of brain tumor, the infection rate was 5.22. A total of 46 pathogenic bacteria were isolated from the infected patients, of which 14 were Gram-positive bacteria (30.44%), 31 Gram-negative bacteria (67.39%) and 1 fungus (2.17%).The resistance rate of gentamicin, imipenem and meropenem was higher, the resistance rate of gram-positive bacteria to vancomycin, erythromycin and rifampicin was higher; cerebrospinal fluid leakage,The operative duration 鈮，

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