经Poppen入路手术切除松果体区肿瘤效果的初步探讨

发布时间：2018-04-10 03:19

本文选题：松果体区　切入点：肿瘤　出处：《山东大学》2014年硕士论文

【摘要】：目的初步探讨经Poppen入路手术切除松果体区肿瘤与其他术式相比手术效果的差异。方法回顾性分析2010年8月至2013年10月期间在山东大学齐鲁医院初次诊断并治疗的62例松果体区肿瘤患者的临床资料,将病例分为手术组和非手术组,手术组根据手术方式不同可分为侧脑室腹腔分流术、陶氏分流术、神经内镜辅助下第三脑室造瘘术+肿瘤活检术,幕下小脑上入路松果体区肿瘤切除术、经枕经小脑幕入路松果体区肿瘤切除术、经胼胝体后部入路松果体区肿瘤切除术等,根据术中所见及术后影像学检查(头颅CT或MRI),使用统计学方法检验经Poppen入路切除松果体肿瘤与其他手术方式的差异性。以“松果体区肿瘤”、“入路”、‘"Poppen"、"显微解剖”等作为关键字在Pubmed、中国知网等网站收集一系列有关于松果体区肿瘤手术治疗的相关文献,广泛搜索已发表的包含手术切除程度、对周围结构损伤等结果的中文及英文文献,统计分析所收集的数据以了解各种手术方式的差异性。结果经Poppen入路手术切除松果体区肿瘤与其他手术方式相比在全切率统计学比较P0.05,有统计学意义,初步认为经Poppen入路全切除松果体区肿瘤的全切率优于其他手术方式；经Poppen入路通过脑生理间隙进入,不损伤脑组织,手术创伤小；经Poppen入路术后并发症少,治疗效果好。结论经Poppen入路是治疗松果体区肿瘤较安全且有效的最佳入路之一,经脑生理间隙进入,手术暴露效果好,创伤小,并发症少,治疗效果好。
[Abstract]:PurposeObjective: to explore the difference of surgical effect between Poppen approach and other surgical methods for pineal region tumor resection.MethodThe clinical data of 62 patients with pineal region tumor diagnosed and treated in Qilu Hospital of Shandong University from August 2010 to October 2013 were retrospectively analyzed. The patients were divided into operative group and non-operative group.According to the different operation methods, the operation group could be divided into three groups: lateral ventriculoperitoneal shunt, Dow shunt, neuroendoscope-assisted third ventriculostomy tumor biopsy, supratentorial superior cerebellar approach for pineal region tumor resection.Resection of tumors in pineal region via occipital approach via tentorium cerebellum, resection of tumors in pineal region via posterior approach of corpus callosum, etc.According to the intraoperative and postoperative imaging examination (CT or MRI), the difference of pineal tumor resection via Poppen approach and other surgical methods was examined by statistical method.Using "pineal region tumor", "approach", "Poppen" and "microanatomy" as keywords, we collected a series of related literatures on surgical treatment of pineal region tumor on Pubmed. China.com.In order to find out the difference of surgical methods, the published Chinese and English literatures including the degree of surgical resection and the results of peripheral structure damage were searched extensively. The collected data were statistically analyzed.ResultCompared with other surgical methods, the total removal rate of pineal region tumors by Poppen approach was significantly higher than that of other surgical methods (P 0.05). It was considered that the total removal rate of pineal region tumors via Poppen approach was better than that of other surgical methods.Poppen approach through the brain physiological space, no damage to brain tissue, the operation injury is small, the Poppen approach has few complications and good therapeutic effect.ConclusionPoppen approach is one of the most safe and effective approaches to the treatment of pineal region tumors. It has a good effect of surgical exposure, less trauma, less complications and better therapeutic effect through the brain physiological space.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R739.41

【参考文献】