以多颅神经损害为首发症状的神经结节病1例报告

发布时间：2018-04-15 00:28

本文选题：神经结节病 + 多颅神经损害　；参考：《中风与神经疾病杂志》2017年04期

【摘要】：正结节病(sarcoidosis)是一种原因不明的非干酪样坏死性上皮细胞肉芽肿为病理特征的系统性疾病~([1,2]),主要累及肺及淋巴结,也可表现为多系统受累,女性多于男性,其临床症状多不典型,易致漏诊、误治,活检组织病理学检查是目前确诊结节病的金标准~([3,4])。仅3.5%~5%的结节病累及神经系统~([5,6]),即神经结节病,其中50%~75%可导致颅神经病变,以面神经麻痹最常见~([7]),其中第V、VI、IX、X对颅神经很少受累~([8,9])。现报道1例以多颅神经损害为首发表现的神经结节病。1病历资料患者,女性,55岁,因"双下肢乏力6 d,双眼睑闭合不全、声嘶4 d余"于2016年7月30日入住南昌大学第二附属
[Abstract]:It is for sarcoidosis (sarcoidosis) pathological features of systemic disease is an unexplained non caseating epithelial cell granuloma ~ ([1,2]), mainly involving the lung and lymph nodes, but also can be expressed as multi system involvement, more women than men, the clinical symptoms are not typical, easily lead to misdiagnosis and mistreatment. Biopsy is the gold standard for diagnosis of sarcoidosis ~ ([3,4]). Sarcoidosis nervous system only 3.5%~5% ~ ([5,6]), which can lead to nerve sarcoidosis, which 50%~75% cranial nerve lesions, with facial nerve paralysis is the most common ~ ([7]), the V, VI, IX, X of cranial nerve rarely involved ~ ([8,9]). We report 1 cases of multiple cranial nerve damage to nerve sarcoidosis.1 medical records of patients, the first manifestation of female, 55 years old, because of the weakness of lower limbs 6 D, eyelid dysraphism hoarseness, 4 more than D in July 30, 2016 admitted to the Nanchang University Second Affiliated

【作者单位】：南昌大学第二附属医院神经内科;南昌大学第二附属医院呼吸科;南昌大学第二附属医院影像科;
【分类号】：R747.9;R593.9

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