乳果糖联合白醋灌肠预防消化道出血后肝性脑病的疗效及对神经功能的影响

发布时间：2018-04-16 10:09

本文选题：神经功能 + 肝性脑病　；参考：《中国实用神经疾病杂志》2016年24期

【摘要】：目的分析乳果糖联合白醋灌肠预防消化道出血后肝性脑病的疗效及对其神经功能的影响。方法选取我院收治的72例肝硬化合并消化道出血患者,采用随机数字表法分为观察组(n=36)和对照组(n=36),2组均给予乳果糖治疗,观察组加用白醋灌肠治疗,比较2组疗效、治疗前后BA、ALT、DST、NCT指标及肝性脑病发生率。结果观察组总有效率为86.11%(31/36),高于对照组的63.89%(23/36),差异有统计学意义(χ2=4.741,P0.05);与对照组相比,观察组治疗后BA和ALT改善程度较大,差异有统计学意义(P0.05);与对照组相比,观察组治疗后DST较高,NCT较低,差异有统计学意义(P0.05);观察组肝性脑病发生率(2.78%)低于对照组(22.22%),差异有统计学意义(χ2=4.571,P0.05)。结论乳果糖联合白醋灌肠预防消化道出血后肝性脑病,能够提高患者智力,改善患者神经功能,降低肝性脑病发生率,值得推广应用。
[Abstract]:Objective to analyze the effect of lactulose combined with white vinegar enema on the prevention of hepatic encephalopathy after gastrointestinal hemorrhage.Methods Seventy-two patients with liver cirrhosis complicated with gastrointestinal hemorrhage in our hospital were randomly divided into two groups: the observation group (n = 36) and the control group (n = 2) were treated with lactulose, the observation group was treated with white vinegar enema, and the curative effect was compared between the two groups.Before and after treatment, the NCT index and the incidence rate of hepatic encephalopathy were detected.Results the total effective rate of the observation group was 86.11g / 36, which was significantly higher than that of the control group (63.89 / 23 / 36) (蠂 ~ 2 / 4.741 / P 0.05). Compared with the control group, the improvement of BA and ALT in the observation group was greater than that in the control group (P 0.05), and the difference was statistically significant compared with the control group.The incidence of hepatic encephalopathy in the observation group was lower than that in the control group (P < 0.05), and the incidence of hepatic encephalopathy in the observation group was lower than that in the control group (P < 0.05).Conclusion the combination of lactulose and white vinegar enema in the prevention of hepatic encephalopathy after gastrointestinal hemorrhage can improve the intelligence of patients, improve the neurological function of patients, and reduce the incidence of hepatic encephalopathy, which is worth popularizing.
【作者单位】：河南漯河市中心医院消化内科;
【分类号】：R747.9;R57

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