显微手术联合伽马刀对窦旁脑膜瘤的治疗效果研究及安全性评价

发布时间：2018-04-18 01:37

  本文选题：显微手术 + 伽马刀　； 参考：《临床医学研究与实践》2016年21期

【摘要】：目的探讨显微手术联合伽马刀对窦旁脑膜瘤的治疗效果及安全性。方法选取2010年2月至2011年2月我院收治的50例窦旁脑膜瘤患者,按照手术治疗方式的不同分为两组,对照组(20例)采用常规手术治疗,观察组(30例)采用显微手术联合伽马刀治疗。比较两组患者治疗后的肿瘤切除率、神经功能评分、并发症发生率、复发率及预后良好率。结果观察组全部行脑膜瘤Simpson Ⅱ~Ⅲ级切除,对照组全部行脑膜瘤Simpson Ⅰ级切除。两组患者治疗前神经功能评分差异无统计学意义(P0.05),治疗后两组患者神经功能评分均显著降低,且观察组神经功能评分显著低对照组,差异具有统计学意义(P0.05)。观察组的并发症发生率及复发率均明显低于对照组,差异有统计学意义(P0.05)。两组患者5年随访结果显示,观察组患者的预后良好率显著优于对照组,差异具有统计学意义(P0.05)。结论采用显微手术联合伽马刀治疗窦旁脑膜瘤可有效提高肿瘤全切率,减少神经功能的损伤和并发症的发生,显著提高患者术后的生存率和生存质量。
[Abstract]:Objective to evaluate the efficacy and safety of microsurgery combined with gamma knife in the treatment of paranasal meningioma.Methods from February 2010 to February 2011, 50 patients with periantral meningioma were divided into two groups according to the different surgical treatment methods. The control group (n = 20) was treated with routine operation.The observation group (n = 30) was treated with microsurgery combined with gamma knife.The tumor resection rate, neurological function score, complication rate, recurrence rate and good prognosis were compared between the two groups.Results all the patients in the observation group were treated with Simpson 鈪，

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