非酮症性高血糖合并舞蹈症6例临床分析

发布时间：2018-04-23 11:12

本文选题：舞蹈症 + 非酮症高血糖　；参考：《中国神经精神疾病杂志》2017年08期

【摘要】：目的探讨非酮症性高血糖合并舞蹈症患者的临床、影像学特点及随访结果。方法对6例非酮症性高血糖合并舞蹈症患者的临床资料、出院后随访结果进行回顾性分析。结果患者的平均起病年龄为(65.83±13.93)岁,其中女性患者5例,男性1例;急性-亚急性病程,患者表现为单侧(n=5例)或双侧肢体(n=1)舞蹈样动作,面部肌肉均有受累(n=6)。入院时静脉血糖平均值为:(9.21±5.15)mmol/L;所有患者的糖化血红蛋白显著升高:(14.1%±3.5%)。所有患者的MRI均提示基底节区T1序列高信号病灶,均累及壳核,可同时合并豆状核、尾状核受累;3例患者磁敏感成像(SWI)序列发现,对应的基底节区病灶为低信号病灶。2例患者发现大脑中动脉重度狭窄。5例患者平均随访(16.2±7.2)个月,3例患者死亡。结论颅脑MRI示基底节区T1加权序列高信号病灶是C-H-BG主要特点;患者可合并对应的SWI序列的低信号病灶。
[Abstract]:Objective to investigate the clinical, imaging features and follow-up results of non-ketotic hyperglycemia with chorea. Methods the clinical data of 6 patients with nonketotic hyperglycemia complicated with chorea were retrospectively analyzed. Results the average onset age of the patients was 65.83 卤13.93 years old, of which 5 cases were female, 1 case was male, and 5 cases were acute subacute disease. The mean venous blood glucose at admission was 9. 21 卤5. 15 mmol / L; the glycosylated hemoglobin of all patients was significantly increased by 14. 1% 卤3. 5%. The MRI of all patients showed that the basal ganglia T1 sequence was hyperintense and involved the putamen nucleus, which could be combined with lentiform nucleus and magnetic sensitive imaging (MRI) sequence in 3 patients with caudate nucleus involvement. The corresponding basal ganglia lesions were low signal lesions in 2 patients with severe stenosis of the middle cerebral artery. The mean follow-up of 5 patients was 16.2 卤7.2 months and 3 patients died. Conclusion brain MRI is the main feature of C-H-BG with high signal intensity on T1 weighted sequence of basal ganglia, and patients can be combined with low signal lesions of corresponding SWI sequence.
【作者单位】：东莞市人民医院神经内科;
【分类号】：R587.2;R742.2

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