中青年隐源性脑梗死合并卵圆孔未闭患者临床及影像特点分析

发布时间：2018-04-25 15:24

本文选题：卵圆孔未闭 + 磁共振成像　；参考：《中风与神经疾病杂志》2016年04期

【摘要】：目的探讨中青年隐源性脑梗死(cryptogenic cerebral infarction,CCI)合并卵圆孔未闭(patent foramen ovale,PFO)患者临床及磁共振成像(magnetic resonance imaging,MRI)特点。方法选取27例18~55岁CCI患者为研究对象,收集其临床资料,采用心脏MRI检测其PFO存在情况,根据结果分为PFO组和非PFO组,对比两组间的临床资料及MRI影像特点差异。结果 27例中青年CCI患者中PFO阳性者13例(48.15%),阴性者14例(51.85%),PFO阳性者房间隔处均可见不同程度的局限性缺损及动态血流信号。PFO组患者具有较低的高血压、高血脂、糖尿病、冠心病病史及颈动脉斑块、脑动脉狭窄阳性构成比,其脑梗死家族史、高同型半胱氨酸血症阳性构成比较高,MRI示其脑梗死病灶主要分布于前循环,以单血供区、㩳2 cm的单发小穿支梗死为主,但两组间各临床资料及梗死灶分布差异均无明显统计学意义(P均0.05)。结论中青年CCI合并PFO发生率较高,多无典型的临床及梗死灶影像分布特征,心脏MRI技术可以作为其检测手段之一。
[Abstract]:Objective to investigate the clinical and magnetic resonance imaging features of young patients with cryptogenic cerebral (CCI) associated with patent foramen ovale (OMQ). Methods 27 cases of 1855 years old patients with CCI were selected as the study subjects, and their clinical data were collected. The presence of PFO was detected by cardiac MRI. According to the results, they were divided into PFO group and non- group. The differences of clinical data and MRI imaging characteristics between the two groups were compared. Results among the 27 young and middle-aged CCI patients, 13 cases were positive for PFO and 48.15%, 14 cases with negative PFO were found to have different degrees of localized defect in the interatrial septum and the patients with dynamic blood flow signal had lower hypertension, hyperlipidemia and diabetes mellitus. History of coronary heart disease, carotid plaque, cerebral artery stenosis, family history of cerebral infarction, hyperhomocysteinemia and hyperhomocysteinemia; MRI showed that the lesions of cerebral infarction were mainly distributed in anterior circulation. The single perforating branch infarction with 2 cm of single blood supply area was the main one, but there was no significant difference in clinical data and infarct distribution between the two groups (P < 0.05). Conclusion the incidence of CCI combined with PFO is high in young and middle-aged people, and there are no typical clinical and infarct imaging features. Cardiac MRI technique can be used as one of the methods for detection of PFO.
【作者单位】：新乡医学院第三附属医院神经内科;平顶山市第一人民医院;解放军第152医院;
【基金】：新乡市重点科技攻关计划基金资助项目(ZG13021)
【分类号】：R743.3

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