帕金森病患者伴发疲劳的相关因素的研究

发布时间：2018-05-07 11:40

  本文选题：帕金森病 + 疲劳　； 参考：《东南大学学报(医学版)》2017年06期

【摘要】：目的:研究帕金森病(PD)患者伴发疲劳的情况及其相关因素。方法:以97例PD患者为研究对象,应用疲劳严重程度量表对患者进行疲劳评估。记录所有患者统一帕金森病量表(UPDRS)评分,Hoehn-Yahr(H-Y)分期,Beck焦虑量表(BAI)、Beck抑郁量表(BDI)、帕金森病睡眠量表(PDSS)、39项PD问卷(PDQ-39)评分及左旋多巴等效剂量(LED),比较疲劳组和非疲劳组之间是否存在差异。结果:97例患者中,63例(63.9%)存在疲劳。UPDRS评分,H-Y分期,BAI、BDI、PDSS、PDQ-39评分及LED与疲劳相关。Logistic回归分析显示,BDI和PDSS评分是疲劳的独立危险因素。结论:PD患者疲劳的发生率高,抑郁和睡眠障碍是影响疲劳的主要因素,严重影响患者的生活质量。
[Abstract]:Objective: to study the prevalence of fatigue in patients with Parkinson's disease (PD) and its related factors. Methods: 97 PD patients were studied. Fatigue severity scale was used to evaluate fatigue. All the patients were assessed with the Unified Parkinson's Disease scale (UPDRS) and the Beck anxiety scale (Beck anxiety scale), the Beck Depression scale (BAIK) and the PDQ-39 (PDQ-39) score and the equivalent dose of levodopa. The differences between the fatigue group and the non-fatigue group were compared between the fatigue group and the non-fatigue group. Results among 97 patients, 63 cases (63.9%) had fatigue. UPDRS score and H-Y stage. LED and fatigue related. Logistic regression analysis showed that BDI and PDSS scores were independent risk factors of fatigue. Conclusion the incidence of fatigue is high in the patients with 1% PD. Depression and sleep disorder are the main factors affecting fatigue and seriously affect the quality of life of the patients.
【作者单位】： 南通大学附属医院神经内科;
【分类号】：R742.5
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本文编号：1856775