不伴感染的老年急性脑卒中患者短时间内降钙素原的变化

发布时间：2018-05-09 14:47

本文选题：急性脑卒中 + 降钙素原　；参考：《中国老年学杂志》2017年24期

【摘要】：目的观察不伴感染的老年急性脑卒中患者短时间内降钙素原(PCT)的变化。方法随机选取老年不伴感染的急性脑卒中患者60例作为研究组,另选取同一时间段来院体检的老年健康志愿者作为对照组。分别观察两组短时间内PCT水平、C反应蛋白(CRP)水平变化和美国国立卫生院神经功能缺损评分(NIHSS)。结果研究组入院24、48 h PCT水平分别为(0.078±0.032)ng/ml、(0.076±0.031)ng/ml,均明显高于对照组[(0.045±0.016)ng/ml、(0.043±0.014)ng/ml,均P=0.000],研究组入院24、48 h CRP水平分别为(5.324±0.124)mg/L、(5.546±0.137)mg/L与对照组[(5.316±0.119)mg/L、(5.512±0.127)mg/L]无统计学差异(P=0.718,0.159)。轻、中和重度缺损组在入院24、48 h PCT水平无统计学差异(P=0.605,0.191)。结论不伴感染的与老年急性脑卒中患者短时间内PCT水平虽然明显升高,与神经功能缺损程度无明显相关性,可以作为鉴别急性脑卒中是否合并感染的重要指标。
[Abstract]:Objective to observe the changes of procalcitonin (PCT) in aged patients with acute stroke without infection. Methods A total of 60 elderly patients with acute stroke without infection were randomly selected as the study group, and the healthy elderly volunteers in the same period were selected as the control group. The changes of PCT level and the neurological impairment score of the National Institutes of Health (NIH) were observed in the two groups in a short period of time. Results the PCT levels in the study group were 0.078 卤0.032 ng / ml, 0.076 卤0.031 ng / ml, respectively, which were significantly higher than those in the control group [0.045 卤0.016 ng / ml, 0.043 卤0.014 ng / ml, P = 0.000]. The CRP levels of the study group at 2448 hours were 5.324 卤0.124 mg / ml and 5.546 卤0.137)mg/L, respectively, and there was no significant difference between the study group and the control group [5.316 卤0.119mg / L / 5.512 卤0.127)mg/L]. There was no significant difference in PCT level between mild, moderate and severe defect group at 24 h after admission (P < 0. 605 ~ 0. 191). Conclusion although the level of PCT in the elderly patients with acute stroke without infection is significantly increased in a short period of time, there is no significant correlation between the level of PCT and the degree of neurological impairment. It can be used as an important index to distinguish acute stroke from infection.
【作者单位】：承德医学院附属医院神经内科;承德市中心医院检验科;
【基金】：承德市科技支持计划项目(No.201422040)
【分类号】：R743.3

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