脑干听觉诱发电位对脑干缺血性进展性卒中早期的预警价值研究

发布时间：2018-05-12 09:55

  本文选题：脑干听觉诱发电位 + 后循环　； 参考：《蚌埠医学院》2017年硕士论文

【摘要】：目的:分析脑干听觉诱发电位在脑干梗死早期有无异常变化,以及对脑干梗死发生进展有无早期预警价值。方法:对发病24h内入院经头颅MRI确诊为脑干梗死的患者,在入院时行脑干听觉诱发电位检查(BAEP),并在入院时及在病程的48h对患者进行美国国立卫生研究所脑卒中量表(NIHSS)评分,根据两次NIHSS评分结果,且符合入选及排除标准,分为脑干缺血性进展性卒中组(SIP组)与脑干缺血性非进展性卒中组(对照组),比较两组患者刚入院时的BAEP检查结果,以I、Ⅲ、V各波峰潜伏期(PL)和I～Ⅲ、Ⅲ～V、I～V各峰间潜伏期(IPL)为观察指标,并对两组患者BAEP检查结果进行对比分析。结果:1、本研究共完成36例,SIP组18例,其中男性患者10例,女性患者8例,年龄49～82岁,平均年龄72.50±8.91岁;对照组18例,其中男性患者9例,女性患者9例,年龄47～85岁,平均年龄73.06±10.11岁。两组研究对象性别、年龄、高血压、糖尿病等一般资料均具有可比性,即差异无统计学意义(P0.05)。2、对照组BAEP总异常率为83.33%,单侧异常率22.22%,双侧异常率61.11%,主要异常表现是双侧Ⅲ、V波的PL及Ⅲ～V波的IPL延长,SIP组BAEP总异常率为88.89%,单侧异常率22.22%,双侧异常率66.67%,主要异常表现是双侧Ⅲ、V波的PL及Ⅲ～V波的IPL延长;两组BAEP比较发现,其总异常率、单侧异常率、双侧异常率及I、Ⅲ、V波的PL,I-Ⅲ、I-V的IPL异常率差异均无统计学意义(P0.05),但SIP组Ⅲ-V波IPL的异常率较对照组明显升高以及Ⅲ-V的IPL值较对照组明显延长(即差异具有统计学意义,P0.05)。结论:1、BAEP可以作为脑干梗死早期诊断的辅助检查,且异常表现主要是双侧Ⅲ、V波的PL及Ⅲ～V波的IPL延长;2、本研究初步探讨了BAEP与脑干梗死发生进展的关系,发现脑干梗死早期BAEPⅢ～V波的IPL值延长显著者可能容易发生进展,即脑干梗死早期BAEPⅢ～V波的IPL值对脑干梗死发生进展可能有早期预警价值。但由于本研究样本量较小,不具备行多因素回归分析的条件,即不能排除其他潜在的危险因素的影响,今后我们将扩大样本量进一步研究。
[Abstract]:Objective: to analyze the abnormal changes of brainstem auditory evoked potential (BAEP) in the early stage of brain-stem infarction and its early warning value. Methods: brainstem auditory evoked potential (BAEPP) examination was performed in patients with brainstem infarction diagnosed by MRI within 24 hours after the onset of the disease. The stroke scale (NIHSS) of the National Institutes of Health (NIH) was evaluated on admission and 48 hours after the onset of the disease. According to the results of two NIHSS scores, and according to the criteria of admission and exclusion, they were divided into two groups: brainstem ischemic progressive stroke group and brainstem ischemic non-progressive stroke group (control group). The results of BAEP examination at admission were compared between the two groups. I, 鈪，

本文编号：1878143