纹状体内囊梗死大脑中动脉局部磁共振成像的研究

发布时间：2018-05-14 18:39

本文选题：动脉粥样硬化 + 大脑中动脉　；参考：《扬州大学》2014年硕士论文

【摘要】：目的：应用3.0T高分辨磁共振成像(high resolution magnetic resonance imaging, HRMRI)分析纹状体内囊梗死发病机制及病因,并探讨其与斑块的关系。方法：对2013年1月至2013年12月期间在我院神经内科住院的新发纹状体内囊梗死患者19例,基底节区急性腔隙性脑梗死患者21例分别进行了3.0T高分辨磁共振成像(high resolution magnetic resonance imaging, HRMRI),对其病灶同侧大脑中动脉局部进行HRMRI,分析2组局部大脑中动脉病变的发生率,同时,根据局部成像结果将SCI患者再分为局部有斑块组和局部无斑块组,比较分析了两组间血压、血糖、血脂水平,入院时和入院后NIHSS评分、运动障碍加重的发生率。结果： SCI患者同侧大脑中动脉局部病变的发生率(36.84%,7/19)明显高于同侧LI患者(23.81%,2/21)；有SCI大脑中动脉局部斑块的患者较无局部动脉病灶患者初始临床症状重(NIHSS6.57±2.3vs3.77±1.96, P0.05),且前者早期临床运动症状进展的发生率高于后者(71.43%vs16.67%,P0.029),两组之间比较血液LDL-C患者有显著性差异。结论： 1、HRMRI可清晰显示大脑中动脉的管壁结构,并能发现管腔内附着的斑块。 2、SCI中斑块组较非斑块组初始临床症状重,且临床症状更易进展加重,其中LDL-C水平可作为SCI斑块形成的预测指标。
[Abstract]:Objective: The pathogenesis and etiology of striatal intracapsular infarction were analyzed by high resolution magnetic resonance imaging, HRMRI) 3.0T high resolution magnetic resonance imaging, and the relationship between high resolution MRI and plaque was discussed. Methods: From January 2013 to December 2013, 19 patients with newly diagnosed Intrastriatal Infarction were hospitalized in the Department of Neurology in our hospital. 21 patients with acute lacunar infarction in basal ganglia region were treated with 3.0T high resolution magnetic resonance imaging and high resolution magnetic resonance imaging, MRI respectively. HRMRI was performed on the ipsilateral middle cerebral artery to analyze the incidence of local middle cerebral artery lesions in two groups. According to the local imaging results, the patients with SCI were divided into local plaque group and local plaque group. The blood pressure, blood glucose, blood lipid level, NIHSS score on admission and after admission, and the incidence of aggravation of motor disorder were compared between the two groups. Results: The incidence of local lesions of the ipsilateral middle cerebral artery in SCI patients was significantly higher than that in ipsilateral Li patients (36.847 / 19), and the initial clinical symptoms of patients with local plaques of middle cerebral artery with SCI were significantly higher than those without local arterial lesions (NIHSS 6.57 卤2.3vs3.77 卤1.96, P0.05). The incidence of dynamic symptom progression was higher than that of the latter group (71.43 vs 16.67) (P 0.029). There was a significant difference between the two groups in blood LDL-C patients. Conclusion: 1HRMRI can clearly display the wall structure of the middle cerebral artery and the plaques attached in the lumen. (2) the initial clinical symptoms in the plaque group were more severe than those in the non-plaque group, and the clinical symptoms were more easily aggravated, and the LDL-C level could be used as a predictor of the formation of SCI plaque.
【学位授予单位】：扬州大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.2;R743.3

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