丛集性头痛临床特征与疗效观察

发布时间：2018-05-23 18:06

本文选题：丛集性头痛 + 临床特征　；参考：《重庆医科大学学报》2017年10期

【摘要】：目的:分析神经内科门诊丛集性头痛(cluster headache,CH)的临床特征及其治疗。方法:回顾性分析2013年9月至2015年11月我院神经内科门诊CH患者的人口学特征和临床特点,电话回访患者的用药治疗情况。结果:一共收录32例患者,患者平均发病年龄为29.6岁,男女患病比例为1.9:1(男21例,女11例),初次起病到被确诊的平均时间为10.6年。93.8%的患者有有自主神经症状,其中最常见的是头痛同侧流泪(75.0%)。恶心、呕吐、畏光和畏声为较常见的伴随症状,分别占56.3%、28.1%、37.5%和53.1%。所有的患者均为发作性丛集性头痛(episodic cluster headache,ECH),不存在慢性丛集性头痛(chronic cluster headache,CCH)。在头痛前或头痛中均无先兆症状。在本研究中共有21例患者在急性治疗中口服苯甲酸利扎曲普坦,其中13例(61.9%)有效;共有15例患者在预防性治疗中口服泼尼松片,其中12例(80.0%)有效。此外还有7例患者使用维拉帕米作为预防性治疗药物,共有4例(57.1%)有效。结论:和西方国家相比,我国CH患者初次起病到被确诊的时间更长,有待提高医生对CH的认识。
[Abstract]:Objective: to analyze the clinical features and treatment of cluster headache cluster head ache in outpatient department of neurology. Methods: the demographic and clinical characteristics of Ch patients from September 2013 to November 2015 were analyzed retrospectively. Results: a total of 32 patients were included. The average age of onset was 29.6 years old, and the ratio of male to female was 1.9: 1 (21 males and 11 females). The average time from the first onset to the diagnosis was 10.6 years and 93.8% had autonomic nervous symptoms. One of the most common is a headache on the ipsilateral side with tears of 75. 0%. Nausea, vomiting, photophobia and fear of sound were the most common accompanying symptoms, accounting for 56.3% and 53.1%, respectively. All the patients were episodic cluster head ache, and there was no chronic cluster head ache. There are no symptoms of aura before or during headache. In this study, 21 patients were treated with rizatriptan benzoate, 13 of them were effective, and 15 patients were treated with prednisone in prophylactic therapy, 12 of them were effective. In addition, verapamil was used as prophylactic therapy in 7 patients, 4 patients were treated with verapamil. Conclusion: compared with the western countries, the time between the first onset and the diagnosis of Ch patients in China needs to be improved.
【作者单位】：重庆医科大学附属第一医院神经内科;
【基金】：国家自然科学基金资助项目(编号:30970988) 重庆市科技惠民计划资助项目(编号:cstc2013jcsf B10001-2)
【分类号】：R741

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