华佗再造丸联合阿司匹林治疗老年缺血性脑卒中的临床效果

发布时间：2018-05-27 09:19

本文选题：华佗再造丸 + 阿司匹林　；参考：《中国老年学杂志》2017年21期

【摘要】：目的探讨华佗再造丸联合阿司匹林治疗老年缺血性脑卒中的临床效果及作用机制。方法 118例缺血性脑卒中患者随机分为两组各59例。对照组应用阿司匹林治疗,实验组在对照组基础上应用华佗再造丸治疗。比较两组治疗前后临床症状、血脂水平[总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]、氧化低密度脂蛋白(ox-LDL)、8-异前列腺素F2α(8-iso-PGF2α)的变化情况,并评价两组临床疗效。结果实验组总有效率明显高于对照组(P0.05);与治疗前比较,实验组治疗后中医症候积分、TC、TG、LDL-C水平均降低,HDL-C水平上升(P0.05),而ox-LDL、8-iso-PGF2α在治疗后均未见明显变化(P0.05)。结论采用华佗再造丸联合阿司匹林治疗老年缺血性脑卒中具有抗脂质过氧化作用,可有效缓解临床症状,提高疗效,促进患者身体恢复。
[Abstract]:Objective to investigate the clinical effect and mechanism of Huatuo Zaihua pill (Huatuo Zaiwan) combined with aspirin in the treatment of senile ischemic stroke. Methods 118 patients with ischemic stroke were randomly divided into two groups (59 cases each). The control group was treated with aspirin, the experimental group was treated with Huatuo Zaiwan on the basis of the control group. To compare the changes of the clinical symptoms, serum lipid levels [total cholesterol TCU, triglyceride TGG, HDL-CU, LDL-C], oxidized low density lipoprotein (ox-LDLU) 8-iso-PGF2 伪 before and after treatment between the two groups. The clinical efficacy of the two groups was evaluated. Results the total effective rate in the experimental group was significantly higher than that in the control group (P0.05A), compared with that before the treatment, the level of TCU TGN LDL-C decreased significantly in the experimental group after treatment, and the level of HDL-C increased, while ox-LDL 8-iso-PGF2 伪 did not change P0.05a after treatment. Conclusion Huatuo Zaiwan combined with aspirin has anti-lipid peroxidation effect on senile ischemic stroke, which can effectively relieve clinical symptoms, improve curative effect and promote the recovery of patients.
【作者单位】：南京中医药大学附属如皋市中医院药剂科;如皋市中医院内科;
【分类号】：R743.3

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