缺血性脑卒中患者发生脑动脉狭窄的影响因素分析

发布时间：2018-05-27 12:43

本文选题：缺血性脑卒中 + 脑动脉狭窄　；参考：《山东医药》2017年32期

【摘要】：目的探讨缺血性脑卒中患者发生脑动脉狭窄的影响因素。方法选取缺血性脑卒中患者330例,入院后收集年龄、性别、BMI、血脂、血糖、糖化血红蛋白(Hb A1C)等资料;头颈部多层CT血管造影检查显示脑动脉狭窄182例,其中单发血管狭窄77例、多发血管狭窄105例;脑动脉无狭窄148例。采用单因素及多因素Logistic回归分析法分析脑动脉狭窄的影响因素。结果单因素分析结果显示,脑动脉狭窄与无狭窄者性别、BMI、饮酒、脑卒中家族史、TC、TG、HDL、LDL、尿素氮、肌酐比较差异均无统计学意义(P均0.05),年龄、吸烟、高血压、糖尿病、FBG、Hb A1C比较差异均有统计学意义(P均0.05)。多因素Logistic回归分析结果显示,Hb A1C(OR=1.296、95%CI为1.140~1.475、P0.01)、吸烟(OR=1.046、95%CI为1.020~1.070、P0.05)、年龄(OR=1.044、95%CI为1.019~1.060、P0.01)是缺血性脑卒中患者发生脑动脉狭窄的独立影响因素。结论年龄、吸烟、Hb A1C是缺血性脑卒中患者发生脑动脉狭窄的影响因素。
[Abstract]:Objective to explore the influencing factors of cerebral artery stenosis in patients with ischemic stroke. Methods 330 patients with ischemic stroke were selected, and the data of age, sex, BMI, blood lipid, blood glucose, glycated hemoglobin (Hb A1C) were collected after admission, and 182 cases of cerebral artery stenosis were revealed by multi-layer CT angiography in the head and neck, including 77 cases of single vascular stenosis. There were 105 cases of vascular stenosis and 148 cases of cerebral artery stenosis. Single factor and multiple factor Logistic regression analysis were used to analyze the influence factors of cerebral artery stenosis. Results single factor analysis showed that there was no significant difference between cerebral artery stenosis and sex without stenosis, BMI, drinking, family history of stroke, TC, TG, HDL, LDL, urea nitrogen and creatinine. All 0.05), age, smoking, hypertension, diabetes, FBG and Hb A1C were statistically significant (P 0.05). The multifactor Logistic regression analysis showed that Hb A1C (OR=1.296,95%CI was 1.140~1.475, P0.01), smoking (OR=1.046,95%CI 1.020~1.070,), and the age of ischemic stroke patients. Conclusion: age, smoking and Hb A1C are the influencing factors of cerebral artery stenosis in patients with ischemic stroke.
【作者单位】：首都医科大学附属北京朝阳医院;
【分类号】：R743.3

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