侧支循环与缺血性卒中

发布时间：2018-05-30 07:09

本文选题：缺血性卒中 + 侧支循环　；参考：《河北医科大学》2017年硕士论文

【摘要】：缺血性卒中的发病率逐年上升。有研究表明,脑侧支循环的程度可能延迟甚至阻止梗死进展。良好的侧支循环可使患者有更好的临床和功能结局,增加血管再通率,降低梗死后出血性转化的风险,并可能延长血管内治疗的时间窗。这些结果的基本原理是侧支循环在实现血管再通之前保持缺血半暗带的血液供应,减小梗死核心区的范围从而可能有更好的临床结局。近年来,影像学技术不断发展,能更准确地对侧支循环进行评估。了解侧支循环的程度有助于合理选择缺血性卒中的治疗,并提高对临床结局预测的准确性。侧支循环的形成与很多影响因素有关,这些影响因素也决定着“侧支治疗”的方法和效果,“侧支治疗”也成为缺血性卒中治疗的新方向。
[Abstract]:The incidence of ischemic stroke is increasing year by year. Studies have shown that the degree of collateral circulation may delay or even prevent the progression of infarction. Good collateral circulation can make patients have better clinical and functional outcomes, increase the rate of vascular recanalization, reduce the risk of hemorrhagic transformation after infarction, and may prolong the time window of intravascular therapy. The basic principle of these results is that the collateral circulation maintains the blood supply of the ischemic penumbra before the vascular recanalization reduces the size of the infarct core and may have a better clinical outcome. In recent years, imaging techniques have been developed to more accurately assess collateral circulation. Understanding the degree of collateral circulation is helpful to select the treatment of ischemic stroke and improve the accuracy of clinical outcome prediction. The formation of collateral circulation is related to many influencing factors, which also determine the method and effect of lateral branch therapy, and "lateral branch therapy" has become a new direction in the treatment of ischemic stroke.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743.3

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