支架置入与药物治疗症状性弓上颅外动脉狭窄的比较研究

发布时间：2018-06-03 09:20

本文选题：脑动脉疾病 + 脑梗死　；参考：《重庆医学》2017年15期

【摘要】：目的探讨支架置入术与药物治疗对症状性弓上颅外动脉狭窄(SECAS)患者预防卒中复发的效果。方法纳入2010年1月至2014年6月在该院确诊为SECAS所致的脑梗死患者,将患者分为支架置入术治疗组(支架组)和单纯药物治疗组(药物组),药物组予以抗血小板及他汀类药物治疗,支架组在药物治疗基础上予以支架置入治疗,观察术后30d和1年的卒中复发率和病死率。结果出院后1年,两组NIHSS评分治疗前后比较差异有统计学意义(P0.05)。两组治疗1年后的再发脑血管事件率差异有统计学意义(P0.05)。两组随访1年的脑血管意外病死率和全因病死率比较差异均无统计学意义(P0.05)。结论颈动脉支架置入术有利于减少SECAS患者卒中复发。
[Abstract]:Objective to investigate the effect of stent placement and drug therapy on the prevention of stroke recurrence in patients with symptomatic supra cranial artery stenosis (SECAS). Methods the patients were included in the patients with SECAS from January 2010 to June 2014. The patients were divided into stent placement group (support group) and simple drug treatment group (drug group), drug group. They were treated with antiplatelet and statins. The stent group was treated with stent implantation on the basis of drug treatment. The recurrence rate and mortality rate of stroke in 30d and 1 years after operation were observed. The results were statistically significant (P0.05) before and after the treatment of two groups of NIHSS scores after 1 years of discharge. The difference of recurrent cerebrovascular events in the two groups after 1 years of treatment was unified. Study significance (P0.05). There was no significant difference between the two groups of cerebrovascular accident mortality and total cause fatality rate for 1 years (P0.05). Conclusion carotid stent implantation is beneficial to reduce the recurrence of stroke in SECAS patients.
【作者单位】：海南医学院第一附属医院神经内科;
【基金】：国家自然科学基金项目(81460184) 海南省卫生和计划生育委员会医学科研项目(2014-07) 海南省社会发展科技专项项目(SF201301)
【分类号】：R743.3

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