缺血性脑卒中复发与睡眠时长的相关性研究

发布时间：2018-06-07 17:27

本文选题：睡眠时长 + 缺血性脑卒中复发　；参考：《医学研究生学报》2017年07期

【摘要】：目的缺血性脑卒中是威胁人类健康的重要疾病,卒中复发更易造成患者致残及死亡。为明确缺血性脑卒中的复发原因,文中探讨夜间睡眠时长对于缺血性卒中复发的影响。方法回顾性分析2016年3月至2016年10月期间在天津医科大学总医院住院治疗的缺血性脑卒中患者70例,并按照病史分为首发组及复发组。分析入组对象行多导睡眠监测(PSG)结果资料;选取同期20名门诊患者进行PSG监测并作为对照。记录所有研究对象睡眠总时长(TST)、性别及年龄。将年龄、性别、TST作为自变量,缺血性卒中复发作为因变量,进行Logistic多元回归分析。结果复发组TST[(5.59±1.62)h]分别短于初发组[(6.56±0.99)h]及对照组[(7.19±0.61)h],且初发组TST时长短于对照组,差异均有统计学意义(P0.05)。Logistic多元回归分析发现睡眠总时长是缺血性脑卒中复发的独立危险因素;且随着TST的减少,缺血性脑卒中复发的风险越大。结论睡眠时间缩短可能会导致缺血性卒中复发风险增加,需引起临床医师的关注。
[Abstract]:Objective Ischemic stroke is an important disease threatening human health. Stroke recurrence is more likely to cause disability and death. In order to determine the causes of recurrence of ischemic stroke, the effect of night sleep duration on the recurrence of ischemic stroke was investigated. Methods from March 2016 to October 2016, 70 patients with ischemic stroke who were hospitalized in the General Hospital of Tianjin Medical University from March 2016 to October 2016 were analyzed retrospectively and divided into the first group and the recurrent group according to the history. The results of polysomnography (PSG) were analyzed, and 20 patients with PSG in the same period were selected as control. Total sleep duration, sex and age were recorded in all subjects. Age, sex and TST were regarded as independent variables and ischemic stroke recurrence as dependent variable. Logistic multiple regression analysis was carried out. Results TST [5.59 卤1.62h] in relapsing group was shorter than that in primary group [6.56 卤0.99h] and control group (7.19 卤0.61h), and the time of TST in primary group was longer than that in control group (P 0.05). Logistic multiple regression analysis showed that total sleep duration was an independent risk factor for recurrence of ischemic stroke. With the decrease of TST, the risk of recurrent ischemic stroke increased. Conclusion shorter sleep time may lead to increased risk of recurrent ischemic stroke, which should be concerned by clinicians.
【作者单位】：天津医科大学总医院神经内科;
【分类号】：R743.3

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