帕金森病的冲动控制障碍

发布时间：2018-06-11 18:52

本文选题：帕金森病 + 冲动控制障碍　；参考：《重庆医科大学》2014年硕士论文

【摘要】：帕金森病的冲动控制障碍（impulsive control disorders, ICDs）是指在帕金森病患者中出现的一组强烈欲望驱使下，难以自我控制，不顾后果，而做出影响自身或他人的一组异常行为的统称。帕金森病患者的这些反复的、过度的精神行为障碍，，给患者日常生活和社会活动带来严重影响。冲动控制障碍主要表现为病理性赌博、强迫性购物、性欲亢进及强迫性进食等。ICDs的发生与多巴胺替代治疗（dopamine replacement treatment, DRT），尤其是多巴胺受体激动剂（dopamineagonists, DAs）的使用有关。ICDs发病与帕金森病发病年龄、性别、抑郁、猎奇性格特征等有一定相关性。ICDs的治疗可通过减少多巴胺能药物治疗、脑深部电刺激、认知行为疗法等治疗手段缓解。为了进一步研究帕金森病的ICDs，加深临床医师对ICDs的认识，本研究收集国、内外相关文献对帕金森病的ICDs流行病学、病因、发病机制、临床表现、诊断标准以及治疗作进一步探讨。
[Abstract]:Impulsive control disorders (ICDs) in Parkinson's disease (PD) refer to a group of abnormal behaviors affecting itself or others that are difficult to control without regard to the consequences and are driven by a group of strong desires in patients with Parkinson's disease. These repeated, excessive mental behavior disorders in Parkinson's disease have a serious impact on daily life and social activities. Impulsive control disorders are mainly manifested in pathological gambling, compulsive shopping, The occurrence of hypersensitivity and compulsive eating and the use of dopamine replacement treatment, especially dopamine receptor agonists, are associated with the onset of Parkinson's disease, age, sex, and depression. ICDs can be alleviated by reducing dopaminergic drug therapy, deep brain electrical stimulation, cognitive behavior therapy and so on. In order to further study the ICDsof Parkinson's disease (PD) and to deepen the understanding of ICDs among clinicians, the epidemiology, etiology, pathogenesis, clinical manifestations of ICDs in China and abroad were collected. Diagnostic criteria and treatment were further discussed.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R742.5

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